Biomedical subjects

J H Thomassin

Publications and source records attributed to J H Thomassin.

3 recordsLinked to original sources

PubMed1980

Chemical and photoelectron spectrometry analysis of the adsorption of phospholipid model membranes and red blood cell membranes on to chrysotile fibres.

A study of the interaction of phospholipid model membranes and red blood cell membranes with UICC A chrysotile fibres using chemical analysis and photoelectron spectrometry showed that the interaction agreed with an adsorption of the membranes on to the chrysotile fibres. The photoelectron spectrometry analysis allowed the statement that phospholipid model membranes are adsorbed as bilayer. Chemical analysis showed that for each milligram of chrysotile the amount of phospholipids adsorbed was about 155 microgram and the available surface for phospholipids was about 38 m/g. It was established that entire membranes were adsorbed. A mechanism for the haemolytic capacity of chrysotile is suggested.

Adsorption↗

PubMed1980

Surface interaction between chrysotile and solutions (dissolution and adsorption): systematic x-ray photoelectron spectroscopy studies.

To test the reactivity of asbestos in relation to its physical and structural properties, surface analysis was made by X-ray photoelectron spectroscopy. The dissolution kinetics of chrysotile in strong reagents demonstrate two rate-limiting steps for the reaction: Mg2+ diffusion and chemical reaction. In some components of the Krebs cycle and in dilute hydrochloric and in oxalic acids, the reaction is limited by the exchange of Mg2+ in the first mineral layer. The interaction of model phospholipid membranes with chrysotile fibres was also studied; the results are in good agreement with the hypothesis of bilayer adsorption. Photoelectron data for adsorption of ghosts indicate that both proteins and phospholipids must be adsorbed onto chrysotile fibres.

Asbestos↗

PubMed1979

[Adsorption of phospholipids by chrysotile fibers : comparison of data from chemical analysis and photoelectron spectrometry (PSX method)].

The adsorption of dipalmitoyl phosphatidyl choline (DPPC) by chrysotile fibers was carried out by chemical and photoelectron spectroscopy analysis. The adsorption isotherms have shown that maximum adsorption was about 130 microgram of DPPC per milligram of chrysotile. The results are in good agreement with estimates of a bilayer adsorption.

Adsorption↗