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Biomedical subjects

J H Watt

Publications and source records attributed to J H Watt.

9 recordsLinked to original sources
PubMed1995

Acute hypotension associated with terbutaline nebuliser therapy in a traumatic tetraplegic patient during the spinal shock phase. Case report.

Acute hypotension was observed during the spinal shock stage of a 35-year-old C3 complete tetraplegic patient after receiving nebulised terbutaline for respiratory therapy. Nine weeks later, when he had recovered from spinal shock, he again received nebulised terbutaline but there was no significant fall in arterial blood pressure. This case illustrates the possibility of a serious degree of hypotension occurring in such patients with this drug.

Adult↗
PubMed1984

Atrial fibrillation: minimal sampling interval to estimate average rate.

The average heart rate and maximal heart rate (average R-R and shortest R-R intervals) in atrial fibrillation are frequently calculated to assess drug effect. The minimum recording sample to obtain accurate estimates of "instantaneous" average and maximum heart rate has not been established. We analyzed the R-R intervals after a 4 minute ECG recording in 40 supine patients with chronic atrial fibrillation. A "life table" analysis revealed that the average heart rate derived from a 20 second sample of atrial fibrillation approximates (+/- 5%) the true value in an estimated 92.5% of patients. On the other hand, a two minute sample is required to approximate the shortest R-R interval within 5% of the true value in 90% of patients. Studies utilizing average R-R interval and shortest R-R interval as an index of drug response should use electrocardiographic sampling intervals of at least 30 seconds and two minutes respectively.

Aged↗