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J H Ziegler

Publications and source records attributed to J H Ziegler.

16 recordsLinked to original sources
PubMed1982

Effect of dietary restriction on carcass composition and adipocyte cellularity of swine with different propensities for obesity.

Experiments were conducted to determine whether dietary restriction altered body composition and adipocyte cellularity similarly in growing lean (Yorkshire) and obese (Ossabaw) swine. Yorkshire (YR) and Ossabaw (OR) swine were fed 65% of the weekly intake of ad libitum-fed Yorkshire (YA) and Ossabaw (OA) swine for 20 weeks. At 200 days of age, adipose tissue mass was 7-fold lower and muscle mass was 50% lower in YR than YA. However, adipose tissue mass of OR was only 2.6-fold less than OA. Furthermore, muscle mass did not differ between OR and OA. Adipocyte number per carcass was 6-fold higher in YA than YR. No differences in carcass adipocyte number were observed between OA and OR. Dietary restriction resulted in a reduced adipocyte size in both breeds of swine. However, adipocyte size for both dietary treatments was greater for obese than lean swine. When carcass adipocyte number was expressed per Kilogram of muscle, there were no differences among YA, OA, and OR; however, this ratio was lower in YR. These results demonstrate: 1) that alterations in nutrient partitioning as measured by accretion of these tissues are different in lean and obese swine when intake is restricted, 2) that differences in adipose tissue mass of YA and OA are due to differences in cell size, and 3) that muscle growth and adipocyte hyperplasia in swine may have a physiological relationship.

Adipose Tissue↗
PubMed1978

Body composition, in vitro lipid metabolism and skeletal muscle characteristics in fast-growing, lean and in slow-growing, obese pigs at equal age and weight.

Eight slow-growing feral, obese (Ossabaw) pigs were sacrificed at 45 kg live weight and an average age of 170 days and were compared with a group of fast-growing, lean (Yorkshire) pigs fed the same ration and sacrificed at either 45 kg (average age 130 days) or at 170 days (average live weight 90 kg). Body composition and various carcass measurements, in vitro adipose tissue metabolism and muscle composition were measured. At equal weight, the obese pig had a greater percent body fat (40 vs. 23%) and backfat thickness (3.3 vs. 2.0 cm) than the lean. At equal age, the difference in percent body fat was not as great (40 vs. 31%) while backfat thickness was equal. Percent body protein was greater in the lean pigs at either equal weight or equal age. In vitro lipolysis, per 100 mg adipose tissue, was lower in obese pigs than in lean pigs at equal weight. However, obese tissue exhibited a greater lipolytic reaponse to DBcAMP stimulation than adipose tissue from lean pigs at equal weight; basal lipolysis per total fat mass was similar. At equal age, no differences in lipolysis between lean and obese pigs were observed. When compared at either equal age or equal weight, weight of semitendinosus muscle, and measurements of muscle RNA and DNA were greater in lean compared to obese pigs. RNA/DNA ratios were similar at equal weight and age whereas the protein/DNA ratio was lower in lean muscle compared to obese at equal weight. The decreased protein deposition in the obese, slow-growing pigs appeared due to fewer muscle nuclei rather than a decreased cellular capacity for protein synthesis.

Animals↗