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Biomedical subjects

J Hallum

Publications and source records attributed to J Hallum.

5 recordsLinked to original sources
PubMed2001

Chlamydia trachomatis and Pap testing from a single, fluid-based sample. A multicenter study.

OBJECTIVE: To determine the potential for both Pap testing and the Chlamydia direct fluorescence assay (DFA) from a single sample using the fluid-based ThinPrep Pap Test method (Cytyc Corporation, Boxborough, Massachusetts). STUDY DESIGN: Conventional DFA was compared to ThinPrep DFA in a direct-to-vial, double-blinded, multicenter protocol. Cervical scrapings were collected for the ThinPrep Pap Test, and then a second swab was used to collect an endocervical sample for a conventional DFA test. The DFA slide prepared from the ThinPrep Test and the conventional DFA sample prepared from the endocervical swab were evaluated independently. Discrepant cases were adjudicated by testing residual specimens using a Chlamydia direct DNA method. RESULTS: Combining 636 adequate cases (94% of the total collected), 582 (91.5%) were negative on both slides, 43 (6.8%) positive by both and 11 (1.7%) discrepant. The prevalence of Chlamydia was 7.9% based on the conventional DFA method (range, 4.3-10.9%). McNemar's two-tailed test indicated the results not to be statistically different (P > .05). Adjudication favored ThinPrep 45% of the time and conventional 55%. Specimen adequacy favored ThinPrep with high statistical significance (McNemar's test, P > .01). CONCLUSION: A second slide prepared from the same vial of cells as that used for the ThinPrep Pap Test can be used for Chlamydia testing by DFA. Fluid-based collection could allow multiple tests from a single sample.

Adolescent↗
PubMed1981

Racial variations in tests of fetoplacental function.

Fetoplacental function tests discriminated well between poorly grown and well grown fetuses in European mothers. In contrast, apart from human placental lactogen, the individual values of poorly grown Asian fetuses fell within the well grown range. Haemoglobin values rose in the second trimester in European pregnancies associated with poor growth, whereas the values fell in the Asian pregnancies both with well grown and poorly grown fetuses. These observations imply fundamental differences in the aetiology of intrauterine growth retardation in the two races.

Adult↗
PubMed1981

Anthropometric and biochemical changes during pregnancy in Asian and European mothers having well grown babies.

At this hospital, about a third of all mothers are Asian. Although generally they have smaller and lighter babies, many Asian mothers achieve similar standards of intrauterine growth to the European mother. This paper describes the nutritional status of Asian and European mothers having well grown babies. Twenty eight European and 11 Asian mothers, who had a normal past obstetric history and a normal present pregnancy resulting in a well grown baby, were studied throughout pregnancy. At each visit, weight, skinfold thickness, and mid-upper arm circumference were measured and biochemical measurements of nutritional status were performed (serum albumin, transferrin and alkaline ribonuclease, plasma amino acids and nitrogen partition of urine). Asian mothers were fatter than European mothers at booking and put on more fat during the second trimester. At the same time, the biochemical tests suggested that the Asian mothers had a higher plane of nutrition. It seems that if the Asian mothers are well nourished in the second trimester, they can achieve a standard of intrauterine growth comparable to the Europeans.

Adult↗
PubMed1981

Anthropometric and biochemical changes during pregnancy in Asian and European mothers having light for gestational age babies.

An assessment of nutritional status using anthropometric and biochemical measurements was made during pregnancy in 8 European and 15 Asian women who produced babies which were light for gestational age. These results were compared with similar measurements in women of both races with normal or pathological pregnancies (hypertension or bleeding) who produced babies of normal size. European mothers of light for gestational age babies with one exception had pregnancies complicated by pathology. They were heavy and fat but apart from urinary peptide hydroxyproline (which was reduced), no other biochemical measurement was specifically associated with poor intrauterine growth. Asian mothers of light for gestational age babies mostly had pregnancies not complicated by obstetric pathology. They gained less weight and fat during the second trimester and during the third trimester, they had biochemical evidence of a poorer nutritional status. Some of the biochemical changes were also noted in pathological pregnancies even though the mothers gained weight and fat normally and had well grown babies.

Anthropometry↗