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Biomedical subjects

J Harrigan

Publications and source records attributed to J Harrigan.

8 recordsLinked to original sources
PubMed1996

Nursing practice management: muscular dystrophy.

The Nursing Practice Management section displays a health care plan for a student with Duchenne Muscular Dystrophy. Following a brief overview of the pathophysiology of the disorder, a case study is presented from which a nursing process-based plan of care is derived.

Child↗
PubMed1985

Reduction of two voltage-dependent K+ currents mediates retention of a learned association.

A single identified neuron, the medial type B photoreceptor, was isolated by axotomy from the nervous systems of nudibranch molluscs (Hermissenda) which had been exposed to three different training experiences. Paired animals had been trained with repeated paired presentations of light and rotation and random animals with randomized light and rotation; naive animals had no training. A two-microelectrode voltage clamp of axotomized type B somata (separated from all synaptic interactions and impulse activity) was used to measure, with a blind procedure, three distinct ionic currents at least 24 h after the training experience. An early K+ current, IA, and a Ca2+-dependent K+ current, ICa2+-K+, but not a light-induced inward Na+ current, were significantly reduced for the paired as compared to the random and naive animals. The magnitude of ICa2+-K+ reduction was related (again measured blindly) to the degree of training-induced suppression of phototaxis (a measure of the learned behavior) for the paired animals. These data are consistent with previous observations indicating that changes of intrinsic type B membrane properties are an important means for encoding the acquisition and retention of Hermissenda associative learning.

Animals↗
PubMed1983

Diagnostic patterns of family physicians for somatoform, depressive, and anxiety disorders.

Somatic complaints are a common feature of somatoform, depressive, and anxiety disorders. The distinction of these disorders is difficult in the primary care setting when somatic complaints are the presenting symptom. This study compared the characteristics and diagnostic consistency of 142 patients diagnosed by family physicians as having one of these three disorders. Patients were identified by chart diagnoses from 12,900 individuals in a university-based family practice. The results demonstrate that the diagnostic terms hysteria and hypochondriasis (now included under somatoform disorders) are infrequently recorded and poorly distinguished from depression and anxiety. Future research on prevention and treatment will be impeded unless family physicians are provided with improved training in practical and nonstigmatizing means of diagnosing and recording somatoform diagnoses.

Adolescent↗
PubMed1978

Interaction of chemosensory, visual, and statocyst pathways in Hermissenda crassicornis.

Neurons in the cerebropleural ganglia (CPG), photoreceptors in the eye, optic ganglion cells, and statocyst hair cells of the nudibranch mollusk Hermissenda crassicornis responded in specific ways, as recorded intracellularly, to stimulation of the chemosensory pathway originating at the tentacular chemoreceptors as well as to stimulation of the visual pathway originating at the photoreceptors. Synaptic inhibition of photoreceptors occurs via the chemosensory pathway. The possible significance of such intersensory interaction is discussed with reference to preliminary investigation of the animal's gustatory behavior and possible neural mechanisms of behavioral choice.

Animals↗