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Biomedical subjects

J Hartung

Publications and source records attributed to J Hartung.

At least 127 records · Page 7Linked to original sources
PubMed1984

[Occurrence of phenolic compounds in the dust of swine stalls and henhouses].

Dust-borne phenols and indols were extracted by ethanol from the sedimentation dust of two pig houses (finishing pigs on half slatted floor resp. piglets on deep litter) and a hen house (3-stage battery cages) and analysed by gas chromatography. In the dust of both pig houses 5 compounds (phenol, p-cresol, p-ethylphenol, indole, skatole) and in the hen house 6 compounds (phenol, p-cresol, 2.6-dimethylamine, 3.4-dimethylamine, indole, skatole) were found. The total amounts of the phenolic compounds came to 275 microgram/g dust (finishing pigs), 111 micrograms/g dust (piglets) and 108 micrograms/g dust (hens). Quantitatively in the finishing pig house p-cresol is well to the fore (53% of the total amount), in the piglet house phenol is dominating (50%) and in the hen house 2.6-dimethylphenol dominates distinctly (83%). The sensory evaluation of the two pig houses showed that the odour intensity in the finishing pig house is distinctly higher than in the piglet house. It seems that the decrease of the odour intensity coincides with the decrease of p-cresol. The results show that animal house dust is an important carrier of trace gases including odorants. The possible influence of dustborne phenol and skatole on the animals is discussed with respect to respiratory affections.

Animals↗
PubMed1984

Prevalence of hepatitis B markers in the anesthesia staff of a large inner-city hospital.

Thirty-four of seventy anesthesia staff members from an inner-city hospital evidenced past infection with hepatitis B. This is more than twice the prevalence previously reported for university-affiliated hospitals. Our findings suggest that screening before vaccinating is likely to be cost-effective for senior or foreign-born urban health care personnel in high-risk specialties, and vaccinating without screening is likely to be cost-effective for all persons newly entering high-risk specialties, including anesthesiology.

Anesthesia Department, Hospital↗
PubMed1983

Nitrous oxide increases intraocular pressure after intravitreal sulfur hexafluoride injection.

In anesthetized cats ventilated with oxygen, 0.5 ml of the inert gas sulfur hexafluoride (SF6) was substituted for vitreous. When the ventilating gas was changed to nitrous oxide (N2O) 66%, balance oxygen, intraocular pressure increased from 14.4 to 30.3 mmHg in 19.5 min. When the ventilating gas was changed back to oxygen, intraocular pressure decreased from 29.1 to 12.0 mmHg in 18.1 min. This intraocular pressure change secondary to gas volume alteration may adversely affect therapeutic outcome of ophthalmic surgery. Accordingly, N2O should be avoided in patients during and following intravitreal injection of SF6 for up to 10 days.

Anesthesia↗
PubMed1983

Intracranial and hemodynamic changes after succinylcholine administration in cats.

Bolus injections of succinylcholine (1.5 mg/kg) significantly increased intracranial pressure (ICP) in cats under normal conditions from control levels of 8 +/- 1 mm Hg to 16 +/- 3 mm Hg (+/- SEM, P less than 0.01), and in the presence of artificially increased ICP from control levels of 27 +/- 1 mm Hg to 47 +/- 4 mm Hg (P less than 0.01). These approximately 100% increases in ICP were accompanied by a transitory decrease in mean arterial pressure (approximately 10 sec), followed by a 15-20% increase (P less than 0.05). Pulmonary arterial pressure increased 20-30% (P less than 0.05). These results, when considered in conjunction with results previously obtained in humans, suggest that succinylcholine may be contraindicated in neurosurgical patients.

Animals↗
PubMed1983

Intracranial pressure during nifedipine-induced hypotension.

The effect of nifedipine-induced hypotension on intracranial pressure (ICP) was investigated in cats with normal and artificially increased ICP. Eleven cats were anesthetized with intraperitoneal pentobarbital (25 mg/kg), intubated, and ventilated with nitrous oxide in oxygen. Mean arterial pressure (MAP), heart rate (HR), and mean pulmonary artery pressure (PAP) were continuously recorded. A double 19-gauge needle was inserted into the cisterna magna; ICP was continuously monitored from one needle and the other was used to increase and maintain ICP at 27 +/- 4 mm Hg by infusion of pH-adjusted Ringer's lactate solution. After control measurements were taken, nifedipine was given intravenously in each cat when ICP was normal and increased. Infusion of 96 +/- 12 micrograms (SEM) nifedipine (approximately equal to 33 micrograms/kg) reduced MAP 35-45% for 2.5 +/- 0.8 min when ICP was normal, and for 2.0 +/- 0.6 min when ICP had been increased. When initial ICP was normal, nifedipine-induced hypotension produced a small (2.2 mm Hg) but statistically significant increase in ICP and decrease in cerebral perfusion pressure (P less than 0.01). When ICP was initially elevated, nifedipine-induced hypotension produced a larger increase in ICP (5 +/- 1 mm Hg) and a proportionately larger decrease in cerebral perfusion pressure (P less than 0.01).

Animals↗
PubMed1980

The HIT clinical profile of psychedelic drug users.

Forty-three psychedelic drug users and 39 non-drug users matched by age, sex, and amount of education, were given the Holtzman Inkblot Technique (HIT). Scores were plotted on the HIT Clinical Profile Sheet. Psychedelic drug users scored significantly higher on Movement, Human Abstract, Color, Hostility, Pathognomic Verbalization, and Sex. Cluster analysis of HIT variables showed that reality contact was adequate for both groups. Drug users were shown to be more actively imaginative, to demonstrate a greater capacity for empathy, to fantasize more, and are more likely to act-out their feelings and possess more unconscious hostility. Although drug users gave a greater number of deviant responses, profile analysis contraindicates evidence of psychopathology. In general, the drug users were significantly more inner-directed than the non-users. It was found that plotting mean scores on the HIT Clinical Profile Sheet without statistical analyses does not accurately reflect the degree of differences between groups of subjects.

Adolescent↗