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Biomedical subjects

J Havel

Publications and source records attributed to J Havel.

9 recordsLinked to original sources
PubMed1991

Total degradation of various chlorobiphenyls by cocultures and in vivo constructed hybrid pseudomonads.

Cocultures consisting of strains converting chlorobiphenyls to the respective benzoates or catechols and of chlorobenzoate degraders were investigated for the mineralization of chlorobiphenyls. Stable mixed cultures were obtained with 4-chlorobiphenyl, while those with 2-chloro- or 3-chlorobiphenyl were found to be unstable and released only low yields of chloride. When both sets of enzyme sequences were combined in one organism, Pseudomonas cepacia strain JH230, by conjugative transfer of genes of the biphenyl degradation sequence, the total degradation of 2-chloro-, 3-chloro-, 4-chloro-, 2,4-dichloro-, and 3,5-dichlorobiphenyl was achieved.

Aroclors↗
PubMed1991

[Preservation surgery in splenic injuries at a type II hospital].

In 1986-1989 in the surgical department of the Pelhrimov hospital nine casualties were treated injuries of the spleen by preserving operations of the latter. In three patients the operation formed part of comprehensive treatment in the abdominal cavity and further treatment because of multiple injuries. In two patients the rupture was treated by a stitch with Gelaspon, in one instance by Gelaspon only. Six times splenectomy was performed with subsequent implantation of the tissue into omentum. All patients with the implantations recovered, except one, with out complications on the part of the implant. The authors present the case-history of a patient where on the 13th day day after operation the implant incl. the omentum had to be removed by relaparotomy. The authors did not encounter this complication in the literature. They ascribe it to the greatly reduced immunity of the patient due not only to the splenectomy but also to associated injuries, and thus healing processes facilitating incorporation of the spleen in the new environment were lacking. Despite this in the authors' opinion implantation of lienal tissue into the omentum, corresponding to one third of the original spleen, is a suitable therapeutic method even in district hospitals.

Adult↗