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Biomedical subjects

J Heiden

Publications and source records attributed to J Heiden.

6 recordsLinked to original sources

Cysticercosis cerebri. Review of 127 cases.

We reviewed the clinical features, diagnosis, and treatment in 127 cases of cysticercosis cerebri. The chief syndromes were seizures (55.1%), hydrocephalus (37.8%), and stroke (11.8%). Serum or CSF indirect hemagglutination titers, determined in 101 patients, were positive in 84.1% of those with CSF pleocytosis but in only 42.1% of those without. Computed tomography (CT), employed in 85 patients, showed typical multiple calcifications in 64.7%. The CT scans were most useful in the surgical treatment of ventriculomeningeal infestation. Ventricular shunt implantation was performed in 40 patients with hydrocephalus and produced marked improvement in 32. Cyst resection was necessary only for patients with rapidly enlarging fourth ventricle cysts.

Adolescent↗

Treatment for severe head injury.

Difficulties in establishing the value of certain treatments for head injury are reviewed. An analysis of 1000 severely head injured patients, managed by varying methods in three different countries, showed that certain treatments were more often used in the most severely injured patients. Even when the severity of injury was taken account of, it appeared that the use of steroids and tracheostomy did not affect outcome; but that patients undergoing mechanical ventilation had outcomes which were worse than expected. The value of treatments proposed for severe head injury needs rigorous scrutiny.

Brain Injuries↗

Prognosis of patients with severe head injury.

The relationship between clinical features of brain dysfunction in the first week after severe head injury and outcome 6 months later has been analyzed for 1000 patients. Depth of coma, pupil reaction, eye movements, and motor response pattern, and patient age prove to be the most reliable predictors. The degree of brain dysfunction changes markedly soon after injury, and more reliable predictions of outcome result when assessment is based on the best level of functioning recorded in each early epoch. Predictions based on very early assessment are, therefore, often unduly pessimistic. Individual predictions of outcome, based on a large data bank, provide a powerful tool for assessing the relative efficacy of alternative treatments.

Adolescent↗

Severe head injuries in three countries.

Methods for assessing early characteristics and late outcome after severe head injury have been devised and applied to 700 cases in three countries (Scotland, Netherlands, and USA). There was a close similarity between the initial features of patients in the three series; in spite of differences on organisation of care and in details of management , the mortality was exactly the same in each country. This data bank of cases (which is still being enlarged) can be used for predicting outcome in new cases, and for setting up trials of management.

Adolescent↗