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Biomedical subjects

J Henker

Publications and source records attributed to J Henker.

At least 37 records · Page 2Linked to original sources
PubMed1989

[History of the human milk collection bank of the Pediatric Department of the Dresden Medical Academy].

The Dresden's milk banking depot was established in 1942. Though there has been a correlation between birth rate and milk quantity collected over the last years, this comparison also points out an unsatisfying willingness of our mothers to nurse their babies. Despite the danger of transferring special infections by raw human milk we will not be able to renounce on this food in special indications in the future.

Academic Medical Centers↗
PubMed1989

[Fecal chymotrypsin concentration in childhood. Normal values, specificity, sensitivity].

The determination of fecal chymotrypsin is a suitable noninvasive screening test for the evaluation of exocrine pancreatic function. Using a photometric assay we found a specificity of 87.5% and a sensitivity of 80%. Beyond the first year of life the lowest limit of normal values is 72 micrograms chymotrypsin/g stool. The method is reproducible, and a 72-hour stool collection is unnecessary when several fecal chymotrypsin determinations in spot stool samples are performed.

Adolescent↗
PubMed1988

[Specificity and sensitivity of the 4-N-acetyl-L-tyrosyl-p- aminobenzoic acid test in childhood with serum p-aminobenzoic acid determination].

Specificity and sensitivity of ALTAB test have been estimated in 40 healthy children and 13 cystic fibrosis patients. The test has been carried out in the modification as 2-hour-serum PABA-test. The found specificity was 90%, the sensitivity 100% respectively. Therefore this test is suitable for evaluation of exocrine pancreas function.

4-Aminobenzoic Acid↗
PubMed1987

[Treatment of severe protracted infantile diarrhea with breast milk].

From 1979 to 1986 we observed 17 infants with a severe protracted diarrhoea. Eleven infants suffered from severe malnutrition. Nearly all patients had lesions of the intestinal mucosa. In all cases treatment with human milk was successful; in 6 infants an initial short-term (3-10 days) total parenteral nutrition was necessary.

Combined Modality Therapy↗
PubMed1987

[Collection and preservation of breast milk].

Milk of the own mother is the best food for young babies. Donated breast milk can be fed in untreated raw condition or after preservation. A microbiological examination is a prerequisite for this. Total bacterial colony counts up to 10 Mpt/l can be considered normal. But premature infants should only be given a highest quality milk with a total bacterial count below 1 Mpt/l. Only coutions milk banking procedures should be used. Deep freezing and lyophilization are the most suitable procedures.

Bacteriological Techniques↗
PubMed1987

[Fatty acid pattern in children with mucoviscidosis in relation to the degree of exocrine pancreas insufficiency].

Fatty acid composition were determined by gas chromatography in serum triglycerides and cholesterol esters of 32 patients (aged 7-17 years) with cystic fibrosis. According to their exocrine pancreas function (determined with secretin-cholecystokinin test), patients were divided in 3 groups. In comparison with previously measured values in 30 metabolically healthy children, patients with cystic fibrosis showed a significantly increased level of palmitic, palmitoleic, stearic, oleic, and linolenic acid in the triglyceride fraction and a significantly increased level of myristic, myristoleic, palmitoleic, stearic, oleic, and triene acid in the cholesterol ester fraction. However, in both fractions, concentration of linoleic acid was significantly decreased. It seems unlikely that malabsorption of ingested fat is responsible for the abnormalities in fatty acid pattern, because no significant differences could be found between the 3 patient's groups.

Adolescent↗
PubMed1986

[Results of small intestinal biopsy studies in childhood and their correlation to other paraclinical findings with special reference to celiac disease].

From 1970 to 1983 1,000 successful peroral intestinal biopsies were carried out at the children's Hospital of the Medical Academy Dresden. No complications such as perforation or bleeding appeared. Peroral intestinal biopsy has a preeminent importance in the diagnostic of coeliac disease. Certain paraclinical parameters in children with coeliac disease were correlated with bioptically recordable small intestinal mucosa changes; from which following results and conclusions can be drawn: Neither reticulin nor gluten antibodies can be recommended as screening parameters for the peroral intestinal biopsy. The determination of reticulin antibodies is better suited for diet checking because of its greater specificity . During the acute phase of coeliac disease 50 per cent of the cases are to be expected to have decreased serum zinc levels. A short-term zinc substitution is to be recommended. An increased number of pathological EEG's can be found in children with coeliac disease; particularly after a longterm gluten-containing diet. Therefore gluten-provocation to diagnose a coeliac disease should be performed after the 6th year of life, this is after completion of the cerebral cell differentiation.

Antibodies↗
PubMed1985

[Serum zinc levels in children with celiac disease].

The gastrointestinal tract is an important organ in the maintenance of zinc homeostasis. We determined the serum zinc level in 140 samples from 78 children with coeliac disease in different phases. Abnormally low values were found only in children with acute coeliac disease (50% below 2 SD), but not in children receiving a gluten-free diet. We therefore suggest to measure the serum zinc concentration in children with coeliac disease and to add a zinc supplementation in patients with diminished zinc values during a period of 2-4 weeks, because zinc deficiency could inhibit the recovery of the intestinal mucosa.

Adolescent↗
PubMed1983

Reticulin antibodies in coeliac disease.

The diagnostic value of demonstrating reticulin antibodies in children affected by coeliac disease is discussed. The antibodies were shown by immunofluorescence in 201 serum samples of 82 patients during the initial phase, during gluten provocation after several months of gluten-free diet. Demonstration of reticulin antibodies is not useful in screening for coeliac disease in patients suspect of the condition since both false positive and negative results occur in spite of the high sensitivity of the test. Determination of the antibodies is, however, a useful guide in dietary control. The antibodies discriminate coeliac disease from cow's milk protein intolerance.

Adolescent↗