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Biomedical subjects

J Hersener

Publications and source records attributed to J Hersener.

7 recordsLinked to original sources
PubMedDate not supplied

[Suture granuloma with calcium pyrophosphate deposits].

In the report two foreign body granulomas, one observed in the fibrous periarticular tissue and the other one in tendo achilles with depositions of crystals inside the granulomas are described. Polarisation microscopy exhibited birefringent crystals which stained black with the van Kossa reaction. The scanning electron microscopic appearance was that of calcium-pyrophosphate-dihydrate when compared with crystals of menisceal tissue in "chondrocalcinosis". The structure of the crystals was different from those that can be observed in calcifying tendinitis or in calcified scars. By X-ray microanalysis nearly identical peaks for calcium and phosphorus were measured, indicating the atomic composition of calcium-pyrophosphate-dihydrate. For the crystalline deposits were restricted to an acellular tissue between the foreign body material it is concluded that necroses in the fibrous periarticular tissues or tendons may be prone for deposition of calcium-pyrophosphate.

Achilles Tendon↗
PubMedDate not supplied

[Destruction of cartilage in the adjuvants disease of the rat].

The structure of cartilage in rats with adjuvant disease was investigated lightmicroscopically and by scanning electron microscopy. Severe destruction of the cartilage with formation of lacunae only was observed in areas previously covered by pannus. However, outside the pannus differences between normal animals and animals with arthritis also were observed. In adjuvant treated animals a more fibrillar structure of the surface was seen as compared with untreated rats. This more fibrillar structure may be due to a loss of mucopolysaccharides. The severe destruction of cartilage must be related to the action of collagenase which only acts in areas with a close contact between cartilage and pannus.

Animals↗
PubMedDate not supplied

[Chondrocalcinosis of the intervertebral disks].

Intervertebral discs removed in cases of disc herniation were investigated by polarized light microscopy. In about 4% of all cases crystalline deposits were detected. The crystals were characterized by different staining methods, scanning electron microscopy and X-ray diffraction. From the results it is concluded that the crystalline deposits are usually composed of calcium pyrophosphate dihydrate. With regard to the age of the patients it became obvious that there was an increased frequency of crystalline deposits with increasing age. Therefore it is assumed that calcium pyrophosphate deposits in intervertebral discs are an agerelated phenomenon as is known from chondrocalcinosis of other joints.

Aging↗
PubMedDate not supplied

[Morphological changes in the articular capsule tissue after preliminary synoviorthesis].

Synovial tissues, surgically removed after synoviorthesis, were investigated microscopically. 198Au metallic desposits were seen until five years after the intraarticular injection. Light fibrotic changes were present, however these tissues exhibited also necrotic changes. 90Y could not be detected microscopically. Inclusions of necrotic cartilage in the synovial membrane may indicate cartilage disturbances due to 90Y. Osmium acid was identified by Xray-microanalysis.

Adult↗