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Biomedical subjects

J Hewitt

Publications and source records attributed to J Hewitt.

At least 199 records · Page 11Linked to original sources
PubMedDate not supplied

The effects of formula change on triglycerides and free fatty acids in preterm infants.

We measured preprandial and 2-h postprandial plasma triglycerides (TG) and free fatty acids (FFA) in 13 preterm infants weekly for 3 consecutive weeks to examine the effects of a premature, medium-chain triglyceride (MCT)-containing formula advancing to a term, long-chain triglyceride (LCT)-containing formula. The infants were on premature formula for the first 2 weeks of the study and were switched to term formula 4-5 days before the last sampling. Significant increases were seen in preprandial and 2-h postprandial TG when the infants were advanced from the premature to the term formula. It was speculated that this increase was due to the predominance of LCT in term formula, which differed in its absorption and metabolism from MCT. Whether these increases persist and if their clinical significance requires further investigation. No consistent change was observed in the preprandial or postprandial FFA.

Fatty Acids, Nonesterified↗
PubMedDate not supplied

A comparison of morning and bed-time ultralente administration when using multiple injections in adolescence.

Ten adolescents took part in a randomized sequential crossover study comparing two insulin regimes: (1) three preprandial injections of soluble insulin from a pen injector plus ultralente given before bed; (2) morning soluble insulin with ultralente, plus two preprandial injections of soluble. Nine patients completed the study. Metabolic profiles were performed at the end of each 3-month treatment period. Glycosylated haemoglobin levels did not fall significantly on either regimen, and there were no differences between the changes in HbA1 concentration on the two regimens. However, blood glucose concentrations tended to be lower with bedtime than with morning ultralente, and were significantly different at 0800 h (13.1 +/- 2.3 mmol/l vs 17.9 +/- 1.9 mmol/l, p less than 0.02) and 1000 h (14.5 +/- 1.4 mmol/l vs 18.6 +/- 0.7 mmol/l, p less than 0.03). Plasma free insulin concentrations were not different. Total daily insulin dose and the proportion of ultralente given in each regimen did not differ. Results indicate that the rise in early morning fasting blood glucose concentrations was less when ultralente was given at bedtime rather than in the morning.

3-Hydroxybutyric Acid↗
PubMedDate not supplied

Improving nursing care through mentored research: a paper within a paper.

In 1995 Western Sydney Area Health Service (WSAHS) and University of Western Sydney Nepean (UWSN) entered a strategic alliance to develop a nursing research culture in Western Sydney. As a result, the WSAHS/UWSN Professorial Nursing Unit (PNU) was established in 1996: Its mandate was to develop a variety of strategies to promote a nursing research culture in the area. One of these strategies was to encourage mentored research projects between personnel in the PNU and inexperienced clinical nurses. This paper describes one such project. In addition, it contextualizes the study in relevant literature relating to mentored research and outlines both the issues and the benefits associated with such projects.

Attitude to Health↗