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Biomedical subjects

J Hewitt

Publications and source records attributed to J Hewitt.

At least 145 records · Page 8Linked to original sources
PubMed1975

[Migrant eruptions in lupus erythematosus. Apropos of a case of lupus erythematosis gyratus repens].

Rare cases of migrant circinated eruptions occurring during the course of lupus erythematosus have been published so far. They have been classified in two categories: 1) supposed toxicodermias due to antimalarials; 2) real cases of erythema annulare centrifugum, mostly inaugurating the L. E. In an exceptional case, a migrating eruption looking like an erythema annulare with a complicated pattern on the trunk, neck and limbs, took place between two rashes of typical L.E. The exact nature of this eruption, clinically and histologically atypical, and its relation with the L.E. itself, have been discussed.

Aged↗
PubMed1975

[Skin pigmentation after amiodarone administration. Histogenetic problems].

The authors present a pathological study of the skin in a 62 year-old man with facial pigmentation due to amiodarone. They found under the light microscope, cells resembling histiocytes filled with pigment. They were less numerous than usually reported, but were found associated with a pericapillary and periglandular lymphocytic infiltration, which raises the problem of iatrogenic lupus or Jessner-Kanoff's disease. Examination under the electron microscope, permitted identification of 5 groups of granulations, three of which had already been observed by Mrs. Fagola. These pigments correspond to lipofuscins, melanin, but also yet unidentified substances, may be metabolites of amiodarone.

Amiodarone↗