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J Hicklin

Publications and source records attributed to J Hicklin.

11 recordsLinked to original sources
PubMed2000

Convergent validity of alternative MMPI-2 personality disorder scales.

The Morey, Waugh, and Blashfield (1985) MMPI (Hathaway et al., 1989) personality disorder scales provided a significant contribution to personality disorder research and assessment. However, the subsequent revisions to the MMPI and the multiple revisions to the diagnostic criteria sets that have since occurred may have justified comparable revisions to these scales. Somwaru and Ben-Porath (1995) selected a substantially different set of items from the MMPI-2 (Butcher, Dahlstrom, Graham, Tellegen, & Kaemmer, 1989) to assess Diagnostic and Statistical Manual of Mental Disorders (4th ed.; American Psychiatric Association, 1994) personality disorder diagnostic criteria. In our study, we compared the convergent validity of these alternative MMPI-2 personality disorder scales with respect to 3 self-report measures of personality disorder symptomatology in a sample of 82 psychiatric outpatients. The results suggested that Somwaru and Ben-Porath's scales are as valid as the original Morey et al. scales and might be even more valid for the assessment of borderline, antisocial, and schizoid personality disorder symptomatology.

Adult↗
PubMed1997

Distribution of disease in cystic fibrosis: correlation with pulmonary function.

STUDY OBJECTIVE: We hypothesized that the radiographic distribution of disease is important in determining pulmonary function, with the lower lung zones of more importance than the upper lung zones. To test this hypothesis, we retrospectively studied patients with cystic fibrosis, a disease with a known proclivity for the upper lung zones. SUBJECTS AND METHODS: Two hundred seventy-six chest radiographs obtained at 2- to 3-year intervals from 51 patients were scored by two radiologists using a 100-point visual severity scale. The distribution of disease was assessed by dividing the lungs into four equal horizontal zones and scoring each zone for the severity of disease. There were 146 concurrent chest radiographs and pulmonary function tests from which multiple linear regression was used to correlate these zonal scores with FEV1/FVC percent predicted. RESULTS: There was excellent interobserver agreement, intraclass correlation coefficients >0.7. The distribution of disease became predominant in the upper lung zones as the patients aged. Although the median score in the upper lung zones was nearly twice that of the lower lung zones, the lower lung zones were nearly three times (partial F ratio; 6.9 lower zone score vs 2.4 upper lung zone score) as important in determining pulmonary function. CONCLUSION: The regional distribution of disease is important in determining pulmonary function. Sparing of the lower lung zones is important in preserving pulmonary function.

Adolescent↗
PubMed1975

Positional information and pattern regulation in Hydra. Dynamics of regions at the boundary.

The dynamics of boundary regions have been investigated mainly by axial grafting and with the emphasis on the head end. The time to resist inhibition of head-end formation and the ability to inhibit head-end formation have been assayed under a variety of conditions. The times increase with distance from the head end. The times required by a boundary region to aquire the inhibitory properties of a head end are longer than those required to aquire resistance to inhibition. Determination of a head end is faster at a cut surbface and at higher temperatures. The results are discussed in terms of a model involving two gradients. Some anomalous results are reported.

Animals↗
PubMed1975

Positional information and pattern formation in Hydra. Dynamics of regions away from the boundary.

The dynamics of regions away from the head-end boundary have been investigated by a variety of assays, and the changes appear to be slow. If, for example, a head end is grafted onto a peduncle to give H/56F, region 5 does not become a region 1 with 72 h. Such results support a gradient type model, and exclude a head end inducing a region 1 in the tissue adjacent to it. The changes can be interpreted if the positional value were effectively slowly diffusible: about 10 times more slowly than the positional signal. The results also have implications for studies on polarity reversal.

Animals↗