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Biomedical subjects

J Hildell

Publications and source records attributed to J Hildell.

At least 37 records · Page 2Linked to original sources

Evaluation of transplanted kidneys with computed tomography and ultrasound.

165 computed tomography (CT) and 98 ultrasound (US) examinations were performed in 64 renal transplant patients. The correlations between CT/US, contemporary clinical and retrospective diagnoses were analysed. CT and US are of great help in the post transplantation follow up, particulary when used together. Determination of the cause for unsatisfactory transplant function had always constituted one of the major problems for the clinician involved in the care for organ transplant patients. Traditionally transplant malfunction had been investigated by clinical examination, renography, radionuclearscanning, angiography and needle biopsy. (Nilsson et al. 1968. Starzl et al. 1970. Häyrö 1981). Computed tomography (CT) and ultra sound scanning (US) show promising capacities to differentiate between the alternative causes for diminished transplant function. (Frick et al. 1981, Smith 1981). The purpose of this presentation is to evaluate CT and US in the diagnosis of the various conditions causing impaired function of the transplanted kidney.

Acute Disease↗

Radiographic appearances in Crohn's disease. III. Colonic lesions following surgery.

Posteroperative films of 114 patients subjected to a primary operation for Crohn's disease were reviewed with special regard to postoperative lesions in the colon. Recurrence in the colon was in 13 patients of 16 due to an exacerbation of the disease in segments left behind at operation. Recurrence in the new distal ileum in addition to persistent colonic disease occurred in 11 patients of 12. This was probably due to the operative connection of the ileum to a diseased colon.

Colitis↗

Percutaneous nephrostomy. Aspects on clinical application.

During a 6-year-period percutaneous nephrostomy has been used for supravesical urinary diversion in 115 patients and 132 individual kidneys. The procedure proved to be a safe and effective alternative to operative nephrostomy in patients with urinary obstruction but may be used also in other urologic conditions.

Adult↗

Radiographic appearances in Crohn's disease. IV. The new distal ileum after surgery.

Postoperative films of 150 patients operated upon for Crohn's disease were reviewed with regard to postoperative abnormalities in the new distal ileum. The lesions were always located in the most aboral part of the ileum. In patients with persistent colonic disease the ileal lesions were apparently the result of a spread of colonic lesions. In many of the remaining patients there was strong evidence that recurrent disease was representative of persistent disease.

Colectomy↗

Predictive value of small bowel radiography for recurrent Crohn Disease.

Small bowel radiographs of 53 patients who had remote surgery for Crohn disease were reviewed. In 10 of these, the radiographic studies could be compared with pathologic specimens from recent reoperations. The correlation of radiographic features and photographic and histopathologic alterations in these specimens was very close. Normal radiographs were found in 21 patients. In the other 32 patients, various types of inflammatory lesions were recorded. Submucosal edema was seen as broad folds in 23 patients, as irregular folds in 10 patients, and as absence of mucosal folds in nine patients. Superficial ulcerations were seen in 22 patients. Transmural lesions were seen in 14 patients but were seldom pronounced. Patients with normal postoperative small bowel radiographs had no signs of clinical recurrence, whereas 27% (4/15) of those with submucosal edema and superficial ulcerations had clinical signs of recurrence. In 87% (13/15) of patients with transmural lesions, there was clinical recurrence. Local progression could be documented in two of 20 patients. There were no instances of axial progression. Postoperative small bowel radiography seems to have useful predictive value for recurrent Crohn disease.

Adult↗

[Sequence-CT: early enhancement--curves of the healthy kidney].

Ten healthy kidneys were studied by sequence-scans every 15 seconds following i. v. bolus-injection of metrizoate. Enhancement of renal cortex, medulla and the abdominal aorta was measured separately. The curves of the renal parenchyma are summations of three functions: perfusion, diffusion of contrast agent to the interstitial fluid, and accumulation of the enhanced urine and its excretion. The enhancement-curves of the aorta and of the renal cortex show two peaks due to recirculation and high perfusion. The curve of the renal medulla is characterized by a slow rise and lower and wider single peak. Knowledge of the normal enhancement-curves is essential for the evaluation of altered renal perfusion.

Contrast Media↗

Ultrasonic evaluation of palpable abdominal masses.

Fifty patients presenting an abdominal mass was investigated with ultrasonography as the first examination. In 5 patients no mass was found by ultrasonography and repalpation revealed no abnormal findings. Of the 45 patients with a mass, ultrasound verified the mass in 43 patients (96%) and a correct origin of the mass was found in 41 patients (91%). The exact nature of the lesion was diagnosed in 32 patients (71%). In 2 patients ultrasonography was falsely negative

Abdominal Neoplasms↗

Percutaneous pyelolithotomy. Case report and technical comments.

A case of nonoperative renal stone extraction through a nephrostomy tract is described. The stone was removed with the aid of a newly constructed device. The advantage of this device over a Dormia stone basket is that it has a steerable tip, which facilitates trapping of the stone in the basket.

Aged↗

Breast hamartomas. An important entity in mammary pathology.

1. Fifteen cases of a rather distinct entity of tumour-like lesion in the breast are presented. 2. They have a distinct mammographic appearance and can be easily shelled out at surgery, leaving symmetrical breasts. 3. They are well-circumscribed lumps of varying size with a smooth surface. 4. Microscopically they show normal or dysplastic glandular structures of lobules and ducts, without neoplastic features, within a prominent fibrous stroma. The lesions appear to be closely related to adenolipomas.

Adolescent↗

Breast cancer screening with mammography: a population-based, randomized trial with mammography as the only screening mode.

A population-based, randomized breast cancer screening project was undertaken using mammography alone. Of 17,447 invited women aged 50-69, 12,765 (73%) attended the screening. On the basis of the screening films, malignancy was suspected in 405 women (3.2%) who were recalled for complete mammography. Additional films showed that the suspicion of malignancy was false in 194 women. The remaining 211 women (1.7%) were referred for clinical and cytological examination. Of these, 159 had surgery. Breast cancer was proved in 97 women, corresponding to a prevalence rate of 7.6/1000. Fifty-three (55%) of the carcinomas were either in situ or invasive with a diameter of less than or equal to 1 cm. Axillary metastases were found in 19 patients (19.6%). Cancers detected at screening were significantly less advanced than those in the control group. There was a remarkably high frequency of tubular carcinoma among cancers detected at screening.

Aged↗

Radiographic appearances in Crohn's disease. I. Accuracy of radiographic methods.

Preoperative films of 176 patients operated upon for Crohn's disease were reviewed and compared with microscopic findings in the resected specimens in order to assess the accuracy of the radiographic techniques used. It was found that a diagnosis of the presence and the extent of the disease was often dependent on the demonstration of minor mucosal ulcers and less marked submucosal edema. These lesions were not adequately demonstrated by any of the techniques used for small bowel examination, but were consistently revealed by the double-contrast technique used for examination of the colon.

Adolescent↗

Mammary hamartomas.

Five cases of mammary hamartoma are described, with special reference to the radiographic features. Hamartomas are well circumscribed lesions composed of normal or dysplastic mammary tissue. They are probably more common than has been anticipated from the literature and are important because they may be confused with other well circumscribed tumors, such as cystosarcoma phyllodes. The radiographic characteristics of hamartoma allows a tentative diagnosis in most cases.

Adult↗

Radiographic appearances in Crohn's disease. II. The course as reflected at repeat radiography.

The course and distribution of the lesions in 174 patients with Crohn's disease were evaluated from preoperative films. In the small intestine the course was locally progressive. Colonic disease involved either the right hemicolon or the entire colon. Fluctuations of mucosal lesions were common and could explain the radiographic finding of segmental and left-sided colitis. Variations in the anatomy of the lymphatic system could explain the varying distribution of the lesions.

Cecum↗

Mammary hamartoma, a benign breast lesion.

Hamartoma or mastoma is a benign breast lesion which is unfamiliar to most clinicians. Five cases with this lesion are presented. It is a rather soft, sharply delineated lump which may cause a considerably asymmetry of the breasts. Radiologically it appears as a circumscribed tumour with homogenous or varying density and at operation the lump is easily enucleated. Histologically it contains normal or dysplastic mammary tissue. It is unilateral and benign. The lesion is now more frequently diagnosed because of increased use of mammography and can be mistaken for a neoplasm. It is therefore important that clinicians and radiologists are acquainted with it.

Adult↗

Gray scale ultrasound and endoscopic ductography in the diagnosis of pancreatic disease.

Seventy-two patients were examined by ultrasonography and endoscopic pancreaticography (ERCP) because of clinical suspicion of pancreatic disease. The following final diagnoses were obtained. Carcinoma of the pancreas: 20 patients; pancreatitis: 27 patients; other diseases: 17 patients; no organic disease: 8 patients. In this series, carcinoma of the pancreas was demonstrated with almost equal efficacy by the two methods used. Cysts in the pancreas were better demonstrated by ultrasonography, while ERCP was superior in demonstrating chronic pancreatitis. The diagnostic results with the exclusive use of one method was not satisfactory, but by combining the two methods an adequate diagnostic accuracy was obtained. Thus in the 47 patients with pancreatic disease, organic abnormalities were demonstrated by the two combined methods in 46 (98%). In 41 of the 47 patients (87%) the exact nature of the lesion could be assessed by combining the two methods.

Adolescent↗

Number of projections in mammography: influence on detection of breast disease.

A total of 491 cases of breast cancer were reviewed to evaluate the diagnostic importance of the three standard projections; craniocaudal, mediolateral, and oblique. With only one projection, 90% of the malignancies would have been detected; with two and three projections the percentages rose to 94% and 95%, respectively. Nonvisualization was due to either juxtathoracic position of the tumor or superimposition of dense tissues. A relation was found between the position of a juxtathoracic tumor and the projection in which it was visualized. The mean diameter of tumors not visible due to superimposition of dense tissues was smaller than that of the whole material. In breast screening programs, use of two projections, the oblique and craniocaudal, is recommended.

Breast Neoplasms↗

Percutaneous nephrostomy. Aspects on applications and technique.

Percutaneous nephrostomy was performed in 32 patients: in 8 patients for permanent and in 24 for temporary drainage. The most common indication was obstruction of the distal ureter due to malignancy. Puncture of the renal pelvis was performed with the aid of fluoroscopy and/or ultrasound. Change to larger catheters was achieved using the Seldinger technique. Complications in the form of bleeding occurred in 5 patients and were in conjunction with repuncture after the initial catheter had slipped out, or occured in connection with change to larger catheters. With the routine use of ultrasound and specially designed catheters the method should be an effective alternative to operative nephrostomy also in the nonemergency patient.

Adult↗