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J Hinglais

Publications and source records attributed to J Hinglais.

12 recordsLinked to original sources

[Non-invasive study of the patency of aortocoronary bypass with pulsed Doppler technic. Preliminary studies].

The pulsed Doppler effect is a non-invasive investigation technique based on the fact that the blood cells moving in a vessel on which ultrasound is incident cause a rebound of different frequency, according to their rate. This technique allows us to measure flow in a "measuring volume", whose size and depth are regulable. It is also possible to collect the signal from one or several aorto-coronary grafts, and to distinguish these from the sorrounding vasculature by their diastolic perfusion. This preliminary study (11 cases) is an attempt to formulate strict procedural criteria by comparison with follow-up arteriography of the grafts. The ease of performance of this investigation should, eventually, make it unnecessary to have to carry out repeated arteriography.

Blood Flow Velocity

Biochemical heterogenity of the left ventricular myocardium: transmural and base-apex gradients on H.E.P. contents of the well oxygenated perfused dog heart.

An investigation into the contents (mumol/g w.w.) of the creatine phosphate (CP) and adenosine triphosphate (ATP) of various myocardial regions was performed on the empty beating isolated blood perfused dog heart. Across the myocardial wall, CP concentration was higher in the outer portion (9.03 +/- 0.18) than in the inner portion (8.59 +/- 0.20) (P less than 0.05). In addition to this transmural gradient, a longitudinal gradient was found: tissue contents of both CP and ATP decrease significantly from the base (CP: 9.70 +/- 0.28, ATP: 5.84 +/- 0.20) to the apex (CP: 8.69 +/- 0.27, ATP: 5.57 +/- 0.17) (P less than 0.01 and P less than 0.05 respectively). The gradients of metabolites in the well oxygenated empty beating heart suggest that a permanent metabolic adaptation to less adequate regional O2 reserves is physiologically operating in the subendocardial layer and the apex region of the left ventricle.

Adenosine Triphosphate