[Lung abscess and bronchiectasis].
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Biomedical subjects
Publications and source records attributed to J Hoevels.
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In three patients with portal venous hypertension and oesophageal varices the effect of domperidone on the haemodynamics of the varices was studied. Following transhepatic catheterisation of the left gastric vein the perfusion of the oesophageal varices before and after the application of domperidone was evaluated angiographically. No decrease of the perfusion of the oesophageal varices secondary to domperidone was observed using this method.
Between November 1983 and July 1988 28 patients with haemoptysis were treated by transcatheter embolisation. Clinical follow-up of 22 patients revealed that 5 patients rebled within 21 days after embolization. Haemoptysis ceased completely in the remaining 17 patients. However, 2 patients rebled after 4 and 12 months, respectively. We observed two transient spinal cord injuries, most likely related to spinal cord ischaemia. In the first patient an intercostal artery was embolised with Ethibloc, in the second patient with Gelfoam. In summary, we can say that due to the inherent risk of spinal cord injury, embolisation should be restricted to patients in whom other forms of treatment failed or proved impossible. Ethibloc may be alternatively used for embolisation.
Aneurysms of the pancreatic arteries are a rare complication of pancreatitis. Most usually they are observed with pancreatic pseudocysts or pancreatic abscesses. In view of the danger of haemorrhage, the diagnosis and treatment of these aneurysms is of considerable clinical significance. Angiography plays a dominant role, since it can demonstrate the source of bleeding and, at the same time, provides effective treatment by means of vascular embolisation. This is illustrated by three examples.
Endogenous TRH levels were determined in plasma obtained selectively via percutaneous transhepatic and femoral catheterization. TRH was measured using a very sensitive RIA method. In the pancreatic veins, internal jugular vein, left testicular vein, and other described veins, normal peripheral levels were found. An involvement of the TRH degrading enzyme (TDE) or a rapid intravasal dilution leading to normal peripheral TRH levels in the veins leaving the brain or pancreas, respectively, is discussed.
Fifty patients were examined to determine whether intraarterial DSA can replace conventional angiography to assess the resectability of pancreatic and periampullary carcinomas. Intraarterial DSA yielded equivalent diagnostic information in 60% of the cases. As a result of contrast-enhanced visualisation of the splanchnic veins intraarterial DSA was superior to conventional angiography in 26% of the cases, whereas in 14% intraarterial DSA provided less information due to motion artifacts.
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In 17 patients with suspected bleeding in the lower intestinal tract 23 scintigraphic studies were performed with Tc-colloid, followed in each case by visceral-artery angiography. Comparison of the two methods with the final clinical diagnosis indicated that angiography was correct in 6 of 23 examinations (26%), scintigraphy in 12 of 23 (52%). All scintigraphically negative results were negative also angiographically. Noninvasive, relatively unstressful scintigraphy should be performed for immediate diagnosis in any case of acute bleeding. Emergency-type angiography is reasonably performed only if scintigraphy is positive.
Contrast medium was injected in the portal vein at a low flow rate via a transumbilical catheter in twelve patients. The distribution of the contrast medium in the liver was investigated by computed tomography. The results of this study demonstrate an incomplete mixture of splenic and mesenteric venous blood in the portal vein. In addition, there is layering of the contrast medium and blood in the portal vein, causing inhomogeneous contrast medium perfusion of the liver.
A double-curve catheter with side-holes was used for intraarterial digital subtraction angiography of the aortic arch and selective angiography of the supraaortic arteries. Applying this technique the same catheter can be used in the majority of cases (approximately 75%) if aortic arch angiography is followed by selective catheterisation of the supraaortic arteries.
The technique of two-plane angiography of femoro-popliteal bypasses with 90 degrees knee flexion is described. Shortening, kinking and stenoses of the bypass are clearly demonstrated by this method.
In digital subtraction angiography (DSA) motion artifacts, artifacts due to overshoot, high contrast enhancement, and long exposure time may result in erroneous evaluation of the vessels. Examples are given to demonstrate and analyse the causes of possible misdiagnoses.
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