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Biomedical subjects

J Holian

Publications and source records attributed to J Holian.

11 recordsLinked to original sources
PubMed2000

Live birth and infant death record linkage: methodological and policy issues.

Using records from Ohio annual vital statistics tapes, we describe a method for linking live birth and infant death certificates and for dealing with late-registered and unregistered births. In our 1985-87 Cleveland and East Cleveland study population, deceased infants with late-registered births were found to be similar to those with timely registered births. Approximately 4.6% of decedents, however, had unregistered births and these tended to be very premature infants from socially disadvantaged backgrounds who died shortly after delivery (including homicides following birth at home). We discuss the policy implications of failing to link infant deaths with unregistered births in studies of birth outcomes.

Adult↗
PubMed1996

Client and birth record linkage: a method, biases, and lessons.

"Due to rising data collection costs and the availability of extant data files, record linkage is becoming increasingly important in evaluation research. We begin by discussing record linkage as a data-generating technique and its applicability to evaluation studies. This paper--part of a larger study assessing the perinatal outcomes of a comprehensive prenatal program for poor, urban women--describes a method for linking client records to live and stillbirth records [in Cleveland, Ohio]. Biases which can enter into the linkage process and general issues which need to be addressed early in an investigation are also discussed."

Americas↗
PubMed1989

Infant mortality and health care in Mexican communities.

Data from the 1976-77 Mexican Fertility Survey show a high degree of correlation among community background characteristics, access to medical services and utilization of health care in a sample of 125 localities. All of these factors are related to infant mortality at the bivariate level. Use of prenatal and infant health care, but not proximity to medical personnel and facilities, is found to affect infant survival independently of the community's degree of socio-economic development. The findings point to the need to employ separate measures of medical access and health utilization.

Adolescent↗
PubMed1975

Human anti-DNA antibody: reference standards for diagnosis and management of systemic lupus erythematosus.

A technique for the measurement of DNA binding activity of sera is described which uses primary internal reference standards in a Farr assay. This allows the DNA binding activity of test sera to be measured in relation to the reference standards and the results are expressed as units/ml. The use of this standardized assay has led to diminished interassay variation and close interlaboratory correlation, and has provided a clinically useful test. In survey using the standardized assay, normal sera were found to have binding activity which did not exceed 15 units/ml; 71% of patients with systemic lupus erythematosus (SLE) had levels greater than 25 units/ml; while only 8% of patients with diseases other than SLE had levels above 25 units/ml. Values between 15 and 25 units/ml appeared to have little diagnostic significance.

Antibodies↗