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Biomedical subjects

J Homolka

Publications and source records attributed to J Homolka.

At least 73 records · Page 4Linked to original sources
PubMed1980

Results of screening for phenylalanine and other amino acid disturbances among pregnant women.

Blood specimens were collected from 15000 pregnant women during the first 3 months of their pregnancy and screened for amino acid disturbances by means of paper chromatography. A high incidence of disturbances in the phenylalanine metabolism was discovered: three cases of mild hyperphenylalaninaemia without phenylpyruvicaciduria (incidence 1:5000); two cases of mild hyperphenylalaninaemia with phenylpyruvicaciduria (incidence 1:7550); four cases of mild phenylketonuria (incidence 1:3750). Disturbances in the metabolism of other amino acids were found to be rare. Metabolic and genealogical findings in some detected families are briefly described.

Adult↗
PubMed1980

[Fructose in ejaculate--correlation with age of proband (author's transl)].

No significant correlation was found to exist between the age of 95 males and fructose level in one millilitre of each one's ejaculate (correlation coefficient 4 = -0.139) nor between proband age and fructose level by volume of ejaculate (r = -1.141). Yet, fructose levels in ejaculate of men below 30 years of age tended quite often to be higher than those recorded from ejaculate of men above 40. The ejaculates tested were different in quality. Close and statistically important negative correlations between proband age and total fructose in ejaculate (r = -0.620) were recordable only from men with excellent average spermatozoan motility, one hour from ejaculation and not even largely reduced after another five hours.

Adult↗
PubMed1979

[Fructose--its importance to quality of human ejaculate (author's transl)].

No statistically significant differences regarding fructose in one millilitre and ejaculated volume were established from a comparison between 95 ejaculates, among them 14 normospermatic, 47 asthenospermatic, 16 oligospermatic with more than ten million of spermia in one millilitre, six oligospermatic with less than ten million, and twelve azoospermatic. Very low and statistically insignificant correlations, also, were found to exist between the fructose level in a given ejaculate and other qualitative parameters, such as volume, sperm count, as well as morphology and motility of spermia one hour and five hours after ejaculation. The correlation coefficient usually was close to zero. These results seem to cast doubt at the diagnostic value of fructose determination in spermatological routine tests. However, studies into the correlations between fructose, glucose and, perhaps, other sugars in both clinically intact males and patients with metabolic disorders might produce new insights into the dynamics of glucose metabolism in ejaculated semen.

Fructose↗