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Biomedical subjects

J Hopfenbeck

Publications and source records attributed to J Hopfenbeck.

3 recordsLinked to original sources

Adaptation in adolescence: the influence of time and severe psychiatric disorder.

This study reports the development of adaptive processes in two groups of adolescents assessed initially and 2 years later with clinical research interviews. Students from a public high school (N = 44) and inpatients on an adolescent psychiatric ward (N = 51) formed the two subject groups. The psychiatrically hospitalized group had significantly improved scores after a 2-year interval on four of six adaptive process Summary Scales: Task Orientation, Relatedness, Self Knowledge, and Inner Synthetic Functions. However, these higher scores did not reach the levels of the high school group at either point of assessment. The scores in the high school group remained stable over time except for an increase in the area of Self Knowledge. The value of this interview-derived assessment, in comparison to other forms of measurement, is discussed, and consideration is given to factors which contribute to the differences between groups.

Adaptation, Psychological

Hepatic vagotomy (partial hepatic denervation) does not alter ingestive responses to metabolic changes.

The effects of transecting the hepatic branch of the vagus nerve were studied in male and female Long Evans rats. No differences between same-sex hepatic vagotomized (HV) and sham operated (SHM) animals were found in postoperative body weight, diurnal patterns of ingestion, or the response to insulin (4, 8, 12 U/kg, IP), 2-deoxy-D-glucose (125, 250, 500 mg/kg, IP), sodium chloride (10 ml/kg: 0.5, 1.0, 2.0 M, IP), or polyethylene glycol (10 ml/kg: 30% w/v, SC). These results can be interpreted as evidence for a minor role of the hepatic vagus in the total complement of hepatic afferent innervation.

Animals