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Biomedical subjects

J Horeau

Publications and source records attributed to J Horeau.

At least 19 recordsLinked to original sources

[Study of the association between aortic coarctation and congenital mitral insufficiency (excluding atrioventricular canals)].

Coarctation of the aorta is accompanied by congenital mitral incompetence in 3% of cases, and this combination worsens the prognosis. A series of 23 cases is reported, and the treatment analysed. In 6 cases only medical treatment was used, either because death was rapid or, on the contrary, satisfactory progress made it possible to wait for the normal age for resection and suture of the coarctation. In one case the severity of the mitral incompetence required early valvular replacement, while the minimal coarctation was ignored. Usually (16 cases) a Crafoord operation is carried out as a first stage, and of the 13 children still alive, 8 had their mitral incompetence improved or stabilised; but in 5 it became worse, requiring mitral valve surgery from 1 to 7 years later. Post mortem study showed the multiplicity of mitral lesions present, and explains the difficulty of mitral 'plasty' operations, which are the best solution in children.

Adolescent↗

[Myocardial biopsy in congestive myocardiopathies of apparently primary origin].

38 patients with congestive cardiomyopathy of apparantly primary origin had a myocardial biopsy. The histology of the fragment of myocardium was studied both by light microscopy and electron microscopy. The results were compared with those from 3 "control" cases and with 16 cases of congestive asystole secondary to a known cause. The non-specific patternss which were observed were of 3 types: patterns of degeneration, pattern of hypertrophy, and interstitial fibrosis. Chronic alcholism had no modifying effect on the ultrastructure. Finally, the group in which the morphology was altered had a higher mortality, but the prognostic significance of the degree of severity of the morphological change must be treated with caution in each individual case.

Adolescent↗

[Phonomechanograms of patients with the Bjork aortic valve prosthesis].

A survey, with consecutive phonocardiograms, of the function of 75 Björk aortic valve prostheses has enabled us to examine the basic components of the opening and closure sounds of this type of replacement; these are usually made up of multiple components in varying combinations. This diversity underlies the importance of an early postoperative recording to act as a baseline. In addition, 2 cases of malfunction presented with only the classical phonocardiographic changes.

Aortic Valve↗

[Endomyocardial biopsy. Innocuousness and clinical value. A 5-year experience].

The authors present their experience of the endomyocardaial biopsy procedure by Konno's technique; they have carried out 180 biopsies in 94 subjects. When the person taking the biopsy is experienced, the procedure is trouble-free, and yields tissue fragments of good quality which are suitable both for histological study and for study of ultrastructure. Biopsies from 47 cases of primary congestive cardiomyopathy have formed the basis of a precise histological study, and have been compared with the findings of a control group comprising various cardiac defects and three normal hearts. The diagnostic and prognostic value of the method are discussed.

Biopsy↗

[Ventricular rhythms with normal heart rate in the acute stage of myocardial infarction].

In relation with 25 personal cases, a general review of ventricular rhythms with normal rate observed during the acute stage of myocardial infarction is undertaken. More commonly called "slow VT", this transient and benign arrhythmia occurs within the first 48 hours of infarction. Presence of numerous fusion beats and His potential recordings make it possible to demonstrate its ventricular origin. Its mechanism is variable: in most cases it results from the discharge of an automatic, non-parasystolic, intermittently active focus, more rarely from the discharge of a parasytolic focus and in many cases, the focus is not apparent. Treatment of this arrhythmia should be careful: its benign character often justifies therapeutic abstention.

Acute Disease↗