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J Huchet

Publications and source records attributed to J Huchet.

34 records · Page 2Linked to original sources
PubMed1986

[Detection during pregnancy of massive fetomaternal transfusion. A life saved by adherence to a protocol].

A case of massive feto-maternal haemorrhage which was discovered by chance in the 34th week of pregnancy is described in detail. This case is characterised by: total absence of clinical, electrical and echographic abnormalities, a part from the fetus being very anaemic; the saving of the very anaemic newborn baby because of the performance of caesarean section; although the pregnant woman was Rh negative, giving her large doses of IgG and anti-D prophylactically seems to have protected her from Rh immunisation. The authors conclude with the special value that they have found using the Kleihauer test. This is a simple, reproducible, low-cost laboratory examination. They suggest that it should be used mainly in the last third of pregnancy and may be even routinely.

Adult↗
PubMed1984

[Collection of anti-D immune plasma after labor. Apropos of 4370 plasmaphereses].

4 370 plasmaphereses have been realized on women in the post delivery period for collection of immune anti-D plasma. 1.550 liters of such plasma have been collected and submitted to Cohn fractionation, leading to the preparation of about 100 000 vials of 100 micrograms. Thus, most of the Paris area needs for anti-D IgG have been covered for the past 13 years. Medico-legal aspects of blood donation at this particular period of a woman's life and proper motivations of these donors are underlined. Prospects for this type of blood collection are analyzed as a conclusion.

Blood Donors↗
PubMed1975

[Fetomaternal hemorrhages and their importance in perinatal pathology].

Transplacental haemorrhage is usually studied as an aspect of Rh immunisation prevention. In this paper the authors emphasize importance of this syndrome in noe-natology, as massive transplacental blood loss may result in severe foetal and neo-natal anemia or even lead to intra uterine death. Different technics for evidencing the presence of fetal cells in the mother's circulation are first discussed, the acid elution method appearing to be the easiest and fastest one. Results of nearly 40.000 Kleihauer's tests screening routinely performed in Paris at the time of delivery, are reported. The much higher frequency of very large transplacental haemorrhage is pointed out in cases of stillbirth. On a practical point of view, routine testing for transplacental haemorrhage finds its major interest in Rh prevention. A formula is proposed by one of the authors to calculate the most accurate dose of passive anti-D antibody in relation with quantitation of fetal haemorrhage. At last the autors attempt a new approach to the problem of neonatal unexplained anemias. Two different types of fetal bleeding are postulated, either chronic associated with haematologic signs of regeneration, or massive at the time of delivery without haematologic symptomatology. These condtions could lead to two different clinical pictures, either hydropsfetalis when chronic, or hypovolemic schock when massive and immediate.

Anemia↗