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Biomedical subjects

J Hulbert

Publications and source records attributed to J Hulbert.

27 records · Page 2Linked to original sources
PubMed1972

Urinary tract infection and oral penicillin G.

The urinary excretion of three oral preparations of penicillin G was measured in six subjects. After a dose of 500 mg of potassium penicillin G the mean urine level was 597 mug/ml in the first of three two-hour periods, 324 mug/ml in the second, and 40 mug/ml between the fourth and sixth hours. Of the dose, 13.4% was excreted in the urine in 24 hours. Differences among the three preparations were not significant therapeutically. Most Gram-negative urinary pathogens are sensitive to 5-50 mug of penicillin G per ml. There is a rational basis for the use of oral penicillini G to treat urinary infection due to Gram-negative bacilli.

Administration, Oral↗
PubMedDate not supplied

The effect of somatic treatment and comorbidity on immediate outcome in manic patients.

Logistic regression was used to determine the association between clinical variables and outcome at discharge in a sample of 438 manics hospitalized at a tertiary care facility. In the total sample, and for males, treatment with electroconvulsive therapy (ECT) and lithium carbonate were positively associated with good outcome. Among females, ECT was positively associated and comorbidity negatively associated with good outcome. Comorbidity appears to be a potentially useful variable in predicting immediate response to treatment.

Adult↗
PubMedDate not supplied

The importance of Axis II in patients with major depression. A controlled study.

Using a naturalistic study design, we compared 76 depressed patients having a DSM-III personality disorder (PD) to a control group of 152 depressed patients with no personality disorder. The patients with major depressive disorder (MDD) and a PD were more likely to have had a younger age of onset, to have had prior hospitalizations, to have a longer duration of episode, to have reported more suicidal thoughts, and to have had more suicide attempts both before and after discharge. Patients with MDD and PD were also more likely to have a family history of alcoholism or antisocial personality and less likely to have dexamethasone nonsuppression, although the latter was not statistically significant. Patients with MDD and PD were less likely to receive electroconvulsive therapy (ECT), equally likely to have received antidepressants, and more likely to receive neither ECT nor antidepressants. Patients with MDD and PD had a poorer response to 'adequate' antidepressants, but a similar response to ECT and 'inadequate' antidepressants. Overall, 91 (60%) of MDD patients and 32 (42%) of MDD plus PD patients were recovered at hospital discharge (X2 = 6.43, P less than 0.025). We conclude that the presence of PD in patients with MDD is associated with a different clinical presentation, family history, and poor recovery at hospital discharge.

Adult↗
PubMedDate not supplied

Working together in rural South Dakota: integrating medical and chiropractic primary care.

OBJECTIVE: To describe the practice of chiropractic in South Dakota and to examine the extent to which they provide primary health care services to the rural population. DESIGN: Survey data from 113 (72%) of the 156 licensed chiropractors in South Dakota (1994). RESULTS: Rural DCs view themselves as primary care physicians and make up one third of the total number of rural primary medical and chiropractic physicians in the state. Rural DCs are more professionally cooperative with medical providers than are urban DCs and, as such, offer services more closely related to primary care. A greater portion of rural DCs, compared with urban DCs, offer in-office laboratory facilities for such services as urinalysis and blood work. Both rural and urban DCs treat large numbers of patients with neuromusculoskeletal (NMS) and non-NMS conditions, with rural DCs being more likely to treat patients with non-NMS conditions, especially skin conditions. CONCLUSIONS: Chiropractors are providing a broad scope of health services in South Dakota, especially in rural areas, indicating that DCs serve as important resources to the South Dakota primary health care system. Chiropractors and general practice medical physicians are increasingly complementing each other in the health care delivery system, especially in rural areas of the state. As such, each profession enhances the system's capacity to offer primary care, with DCs offering primarily NMS care. Continuing increase in the number of medical and chiropractic collaborations is consistent with the imperative to include cooperation with other primary care disciplines to improve health care delivery to rural populations.

Chiropractic↗