PubMed Health⌕ Search

Biomedical subjects

J Hurych

Publications and source records attributed to J Hurych.

At least 19 recordsLinked to original sources
PubMed1978

Effect of intermittent high altitude hypoxia on the synthesis of collagenous and non-collagenous proteins of the right and left ventricular myocardium.

The incorporation of 14C-proline into collagenous and non-collagenous proteins of the right and left ventricular myocardium was investigated in rats exposed to intermittent high altitude hypoxia. Experimental results have shown that even in control animals significant differences exist in the concentration and synthesis of individual protein fractions between the right and left ventricular myocardium. Long-term exposure to intermittent high altitude hypoxia induced a significantly increased concentration of collagenous and non-collagenous proteins in both ventricles. The incorporation of 14C-proline was not affected at this period (ie period of stabilised hypertrophy) in either of the fractions studied.

Altitude Sickness↗
PubMed1978

Influence of pulmonary hypertension on pulmonary diffusing capacity in patients with mitral stenosis.

The pulmonary diffusing capacity (DLCO--steady state method according to Bates and coworkers) was measured at the time of heart catheterization in 12 patients with mitral stenosis without mitral incompetence. DLCO correlates with the tidal volume at rest and during exercise and with pulmonary vascular resistance during exercise only. DLCO and left atrial pressure exhibit a positive correlation up to 22.5 mm Hg only. In patients with mitral stenosis DLCO depends on the alveolar surface area and DLCO is influenced by regional changes in the pulmonary vascular resistance.

Adult↗
PubMed1977

Relations of pulmonary diffusing capacity to ventilation and haemodynamics in healthy subjects.

The pulmonary diffusing capacity (DLCO) was measured in 13 healthy subjects during heart catheterization by the steady-state method (according to Bates and his coworkers). The DLCO shows the closest correlation to the tidal volume at rest, and to the central blood volume during exercise. Further, the DLCO correlates with the cardiac index both at rest and during exercise and with the stroke index at rest only. The DLCO did not show any relationship to the pressures in central circulation, pulmonary vascular resistance, total and alveolar ventilation. Statistical analysis shows that DLCO is most consistently related to the tidal volume at rest, whereas relation to central blood volume is much more stable during exercise.

Adolescent↗
PubMed1977

Predictability of arterial pH and PCO2 from right atrial blood samples in experimental animal.

Arterial and right atrial blood samples were drawn simultaneously under acutely changing acid-base and ventilatory conditions in a series of experiments carried out in nine pigs. The pH, PCO2, bicarbonate concentration and base excess from arterial and right atrial blood are compared. The predictability of the arterial values from the right atrial values is discussed. It is concluded that right atrial blood samples are approximately as informative as arterial blood samples for determining the acid-base status under both normal and acutely changed acid-base and ventilatory conditions.

Animals↗