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Biomedical subjects

J Husted

Publications and source records attributed to J Husted.

28 records · Page 2Linked to original sources

Exercise and breast cancer: review and critical analysis of the literature.

Breast cancer is one of the leading causes of cancer and cancer mortality among Canadian women. Based on the current incidence rates, the National Cancer Institute of Canada has estimated that one in 10 women will develop breast cancer during her lifetime. In an effort to control this disease, various prevention strategies have been proposed. One promising strategy involves the promotion of exercise in healthy women. It has been hypothesized that exercise may protect against breast cancer by influencing regularity of ovulatory cycles, by changing body fat composition, or by enhancing natural immunity. In this paper both the epidemiological and experimental evidence that speaks to a protective effect of exercise is reviewed. Although there are several biologically plausible mechanisms for the association, the existing epidemiological and experimental data are inconclusive due to the small number of studies and their methodological insufficiencies. However, given the enormous potential benefit of even a small protective effect of exercise, further studies designed to address the relationship between exercise and breast cancer risk are warranted.

Adult↗

[General practitioners' attitude to prescription of psychopharmaceuticals. Autonomy versus paternalism, education and understanding of disease].

The object of this investigation was to illustrate the attitudes of general practitioners to prescription of psychotropic drugs and to mental illness. The qualitative research interview method was chosen as the method employed here. Fourteen general practitioners were interviewed while one did not wish to participate. A marked difference was found between the attitudes of the general practitioners to respect the autonomy of the patients or to act paternally. The paternal general practitioner could either prescribe psychotropic drugs on his own initiative or refuse prescription. General practitioners who respected autonomy were relatively restrictive in their prescribing habits so that respect for autonomy was by no means expression for free prescription of psychotropic drugs. Their goal was that the patient should be placed in a situation where he/she could choose and determine personally. The general practitioners considered that their undergraduate and postgraduate training in treating patients with mental illness was inadequate. Taking into consideration how frequently patients with conditions of this nature are seen in general practice, this must be regarded as a serious deficit in medical training. A number of general practitioners have, however, received postgraduate training in this subject. General practitioners did not consider patients who consulted them with mental conditions as mentally ill but they did not have an alternative disease model by which they could classify the problems and complaints of these patients.

Attitude of Health Personnel↗

A measure of the 'sick' label in psychiatric disorder and physical illness.

Persons with psychotic disorders receive devalued labels. Despite considerable theorizing, the proposition that these labels affect the course of psychotic illness has rarely been subjected to investigation. The lack of an adequate operational measure for the labeling construct has hampered research. The present report describes the development of the Social Response Questionnaire (SRQ), a measure of the 'sick' label which incorporates moralistic attitudes, fear of dangerousness and negative expectations attached to the role of the severely psychiatrically ill. This 32-item scale, a multidimensional measure of informal labeling, which may be administered in a self-report format or to significant others, permits the study of dose-response relationships. The SRQ is internally stable. It also exhibits construct validity. Schizophrenics and persons with affective psychosis label themselves and are labeled by others more harshly than persons with Crohn's disease or normals. While self-percepts and the perceptions of significant others are fairly congruent for normals and persons with a significant physical illness, there is no agreement between the self-ratings of psychotics and their significant others. Psychotic persons view themselves more negatively than Crohn's disease sufferers or normals, but not as negatively as their therapists, families and friends. Potential uses for the SRQ in longitudinal research are addressed.

Adolescent↗

Angiographic management of arteriocolic fistulae.

Two cases of massive lower GI bleeding caused by external iliac artery fistulization to the colon are presented. Both patients had had pelvic malignancy and pelvic irradiation. Angiography is the diagnostic procedure of choice. Our cases were successfully treated with local embolization.

Aged↗

Bronchioloalveolar carcinoma: two clinical entities with one pathologic diagnosis.

Bronchioloalveolar carcinoma may present with a variety of radiologic and clinical patterns. Two types of this primary carcinoma of the lung have been recognized: a solitary lesion and a diffuse form. Charts and radiographs of 61 cases of bronchioloalveolar carcinoma were reviewed as well as the pertinent literature. Our experience indicates that the localized form seldom, if ever, becomes diffuse and has a good prognosis following appropriate surgery (lobectomy or pneumonectomy). If the lesion is diffuse, death almost invariably results within 3 years. Based on available clinical information, we suggest that at least two primary tumors of the lung have the histologic pattern of bronchioloalveolar carcinoma: one of these tumors is diffuse and the other is solitary.

Adenocarcinoma, Bronchiolo-Alveolar↗