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Biomedical subjects

J I Craig

Publications and source records attributed to J I Craig.

23 records · Page 2Linked to original sources
PubMed1988

Plasma levels of highly sulphated glycosaminoglycans are raised in patients with chronic myeloid leukaemia.

A study of absolute basophil counts and plasma levels of highly sulphated glycosaminoglycans in 30 peripheral blood samples from 21 patients with different leukaemias was performed. This revealed significantly raised levels of both plasma highly sulphated glycosaminoglycans and basophils in those patients with chronic myeloid leukaemia, as compared to those with other types of leukaemia and 35 normal controls. A strong correlation (r = 0.83) was observed between the levels of highly sulphated glycosaminoglycans and basophil counts in the group as a whole, supporting a direct relationship between the two. The elevated plasma levels of highly sulphated glycosaminoglycans may contribute to the bleeding tendency reported in some patients with chronic myeloid leukaemia.

Adult↗
PubMed1988

Can bone marrow transplantation be offered to more patients in south east Scotland?

The number of patients with haematological malignancies and aplastic anaemia treated by allogeneic bone marrow transplantation in South East Scotland between 1983-1986 is apparently greater than that estimated by the Black Report in 1982. The potential for increasing the use of this effective therapy by using bone marrow donors from the extended family or national volunteer panels is discussed.

Adult↗