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Biomedical subjects

J I Fernández

Publications and source records attributed to J I Fernández.

6 recordsLinked to original sources
PubMed1998

Spontaneous acute abdominal aortic dissection.

A case of spontaneous acute infrarenal aortic dissection, with extension to the right common iliac artery and proximally to just below the origin of the renal arteries is presented. This dissection did not involve the visceral vessels nor the iliac system. The diagnosis was made with ultrasonography and computed tomography, without the need for angiography, and confirmed during surgical intervention, in which, prosthetic replacement of the affected segment was carried out.

Acute Disease↗
PubMed1996

Taurine- and glycine-conjugated bile acids in the preruminant goat: identification by high performance liquid chromatography.

A reversed-phase high performance liquid chromatography technique has been developed for the identification of taurine- and glycine-conjugated bile acids in the bile of preruminant goats. The mobile phase consisted of two solvents: acetonitrile (A) and 5 mM potassium phosphate buffer (pH 4.5) (B). Samples (10 microliters) were eluted with a linear gradient in which acetonitrile was increased from 25 to 35%, and from 35 to 45%, at 10 min intervals. Flow rate was 1.0 ml min-1, and bile acids were detected at 200 nm. This sample high resolution technique was highly reproducible, involved a minimum of straightforward sample treatment, and required a short chromatographic development time. The technique will be of use in the systematic identifications of bile acids in preruminants.

Acetonitriles↗
PubMed1996

Post-natal changes in biliary lipids in suckling goat kids.

The post-natal composition of biliary lipids in the bile of suckling goat kids has been studied during the first month of life. Samples of hepatic and vesicular bile were obtained from animals fed with milk. Bile flow increased with age and the concentration of bile acids also rose up to 14 days of age. Cholesterol reached maximum values immediately after birth and then decreased. Bile acids conjugated with taurine predominated and this pattern of preferential tauroconjugation persisted at all ages, as has also been found in carnivores and sheep. Comparison of vesicular and hepatic bile composition revealed a poor concentration capacity of the gallbladder in pre-ruminant kids.

Aging↗
PubMed1988

Hemodynamic characteristic of the common carotid arteries in diabetic atherosclerotic patients.

Early detection of stenosis is an important task in noninvasive examinations. The authors analyzed 50 patients with diabetic macroangiopathy in lower limbs, but without signs, or symptoms of brain ischemia, and 50 supposedly healthy subjects of similar sex and age composition as control. Eight hemodynamic parameters were measured in the common carotid artery using Doppler ultrasound with spectral analysis. Only 6% of the control group, but 64% of the diabetic patients had two or more altered parameters. The authors conclude that persons with high risk of cerebrovascular disease could be identified by Doppler ultrasound examination of common carotid artery.

Arteriosclerosis↗