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J I Zabala

Publications and source records attributed to J I Zabala.

2 recordsLinked to original sources

[Hemodynamic changes during laparoscopic surgery. Preliminary study].

The haemodynamic changes produced by laparoscopic surgery in children have been evaluated. A transesophageal echocardiographic study on 13 patients (7 males and 6 females, 10.8 +/- 2.7 years old) has been performed before, during and after peritoneal CO2 gas insufflation. A change on the Doppler waves pattern of the infradiaphragmatic veins along with an increase in blood flow velocity were observed. Pulmonary veins suffered minimal changes showing an increase on either the systolic pressure and on atrial contraction. Diastolic retrograde flow in aorta reflected an increase in peripheral vascular resistance. Cardiac output increased minimally. All haemodynamic changes returned to basal after gas peritoneal desufflation. These data show that laparoscopic surgery could produce important cardiac derangements in children with ventricular dysfunction or in patients presenting left ventricular outlet obstruction. In these patients laparoscopic surgery might be precluded.

Abdominal Pain↗

[Secondary effects of prostaglandin E1 on the management of hypoplastic left heart syndrome while waiting for heart transplantation].

OBJECTIVE: Newborns with hypoplastic left heart syndrome (HLHS) included in the heart transplant program depend on continuous prostaglandin E1 (PGE1) perfusion for a prolonged period of time, which can result in various side effects. The objective of this study was to analyze the side effects derived from the use of PGE1 in newborns with HLHS who are awaiting heart transplantation. PATIENTS AND METHODS: Fifteen newborns with HLHS included in a cardiac transplant program between January 1993 and August 1996 were studied. All received continuous endovenous perfusion of PGE1 from the time of diagnosis of the cardiopathy. RESULTS: Thirteen patients were transplanted, with 6 dying in the operating room. Seven survived. Two patients died while waiting for a transplant. All presented short term side effects derived from the continuous perfusion of PGE1, including a slight fever and irritability. However, none of them presented apnea pauses. Cortical hyperostosis and anthral hyperplasia were observed in 13 (83.3%) and 12 (80%) cases, respectively, but in all transplanted cases regression of the anthral hyperplasia was seen after 6 months and regression of the cortical hyperostosis was seen after 12 months. CONCLUSIONS: PGE1 was effective in maintaining the permeability of the ductus arteriosus. The side effects derived from the treatment were well tolerated. The appearance of cortical hyperostosis and anthral hyperplasia is related to the duration of the perfusion and these disappear in the weeks following the suspension of PGE1 treatment.

Alprostadil↗