Chronic idiopathic neutropenia preceding polymyalgia rheumatica and acute myeloid leukemia.
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Biomedical subjects
Publications and source records attributed to J Iakovidou.
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A case of splenic hamartoma is presented that was incidentally discovered in a 55-year-old male during a work-up to determine the aetiology of hypertension. Diagnostic imaging procedures were suggestive of a splenic hamartoma. Histologically, this was found to be of the pulposal type with haemosiderin and calcification foci and many eosinophil leukocytes. The patient had an uneventful recovery. A review of the pertinent references is included, together with a brief discussion about the occurrence of splenic hamartoma in the context of tuberous sclerosis.
A case of a malignant cerebral astrocytoma containing bone in a 56-year old woman is reported. In spite of total removal and radiotherapy the tumour recurred and the patient died 18 months postoperatively. The histological features and immunohistochemical findings are presented. The literature is reviewed and probable mechanisms by which these mesodermal derivatives develop in neuroepithelial neoplasms are discussed.