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Biomedical subjects

J Innes

Publications and source records attributed to J Innes.

29 records · Page 2Linked to original sources

Ultrasonic patterns in vitreo-retinal disease.

The reliability of diagnostic ultrasound in the assessment of vitreo-retinal disease was studied using an all-purpose ultrasonic machine. Five vitreous echo patterns are described, two representing retinal detachment, two demonstrating the features of vitreous membranes (condensation of vitreous tissue) and one typical of simple vitreous haemorrhage. Retinal detachment was correctly diagnosed in over 95% of cases and simple vitreous haemorrhage in 100% of cases. The diagnostic accuracy rate for vitreous membranes was 80--90%. The most frequent source of error arose in the differentiation of localised areas of retinal detachment from fixed dense sheets of preretinal (vitreous) tissue.

Eye Diseases↗

Further studies on the serological effects of C. parvum immunotherapy in cancer patients.

Previous serological studies undertaken in our laboratory have shown that the repeated administration of small doses of C. parvum to a small group of cancer patients resulted in a consistant increase in the levels of IgG (especially the IgG2b subclass), the development of antibodies to C. parvum and the transient appearance of 'rheumatoid factor like' substances in the serum (Br. J. Cancer, 32, 310, 1975). In the present paper we report the results of similar studies in small numbers of (a) inoperable bronchogenic carcinoma patients receiving combined C. parvum and cyclophosphamide therapy, and (b) brain glioma patients receiving intracerebral injection of C. parvum. As might be expected some of the serological changes observed in these patients were not as marked as previously noted. Nevertheless a number of the patients developed autoantibodies which were detectable by the latex and Ripley procedures but not by the Rose-Waaler test. There was no evidence of antinuclear factors by the fluorescence procedure.

Aged↗

A strategy to reduce laxative use among older people.

Institutions can be places of routine and unquestioned practice in the administration of medications. In one mixed ward of psychogeriatric patients constipation was a common problem for which laxatives were routinely given. In this particular ward, many of the patients were receiving up to five different laxatives a day either orally or rectally. Dementia and being bed or chair-bound greatly increased the risk of chronic constipation. Excessive laxative use is another cause of chronic constipation. A review of practice and a decision implement a new approach was prompted by the arrival of new ward managers. The use of laxatives was stopped almost entirely and a new dietary regime was started. This article outlines how the changes were implemented.

Aged↗