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Biomedical subjects

J J Berberich

Publications and source records attributed to J J Berberich.

8 recordsLinked to original sources

The post-cardiac surgery chest radiograph: a clinically integrated approach.

The post-cardiac surgery chest radiograph is often read without full knowledge of the patient's pathophysiology or of the specific surgical approach employed. This lack of clinical integration severely limits the effectiveness of the radiologic consultation. This article synthesizes a pathophysiologic foundation for interpretation, drawing on (1) the preoperative physiology and radiographic findings, (2) the events of surgery, cardiopulmonary bypass, and hypothermia, and (3) a detailed survey of the postoperative occurrences and their radiographic presentations including the various appliances, disturbances in fluid balance and ventilation, and complications encountered in the immediate postoperative period. The objective is to define the perioperative events and their radiographic correlations more accurately so that effective radiologic consultation will result.

Cardiac Surgical Procedures↗

A retrospective analysis of fentanyl and sufentanil for cardiac transplantation.

Drug requirements, hemodynamic responses, and fluid balance were retrospectively studied in 65 male patients undergoing cardiac transplantation. Twenty patients received fentanyl-oxygen (88 +/- 7 micrograms/kg), and 45 patients received sufentanil-oxygen (20 +/- 1 micrograms/kg) as the primary anesthetic technique. The left ventricular ejection fraction averaged 15% and 18%, respectively. Hemodynamic stability was maintained during induction, bypass, and postbypass periods with both drugs. Cardiopulmonary bypass (CPB) was terminated with isoproterenol support for all patients. Additional inotropic support was required for 65% of fentanyl- and 56% of sufentanil-treated patients. Pacemaker support was required less frequently for sufentanil- than fentanyl-treated patients (P less than .01). Vasodilator therapy was required after CPB for patients receiving sufentanil despite the fact that higher-than-anticipated doses of sufentanil were administered during and after CPB. Fluid requirements were similar for both groups. It is concluded that both high-dose fentanyl and sufentanil anesthesia can provide clinically satisfactory anesthesia for cardiac transplantation.

Adult↗

Evidence for increased intrathoracic fluid volume in man at high altitude.

To determine if subclinical pulmonary edema occurs commonly at high altitude, 25 soldiers participated in two consecutive 72-h field exercises, the first at low altitude (200-875 m) and the second at high altitude (3,000-4,300 m). Various aspects of ventilatory function and pulmonary mechanics were measured at 0, 36, and 72 h of each exercise. Based on physical examination and chest radiographs there was no evidence of pulmonary edema at high altitude. There was, however, an immediate and sustained decrease in vital capacity and transthoracic electrical impedance as well as a clockwise rotation of the transpulmonary pressure-volume curve. In contrast, closing capacity and residual volume did not change immediately upon arrival at high altitude but did increase later during the exposure. These observations are consistent with an abrupt increase in thoracic intravascular fluid volume upon arrival at high altitude followed by a more gradual increase in extravascular fluid volume in the peribronchial spaces of dependent lung regions.

Adolescent↗