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J J Breen

Publications and source records attributed to J J Breen.

14 recordsLinked to original sources

Direct measurement of the pK values of an alkaline Bohr group in human hemoglobin.

Proton nuclear magnetic resonance spectra of normal and des-(his 146beta) human hemoglobin in the aromatic resonance region have been compared at different pH values. From these measurements, a pK value for histidine 146beta of 7.1 in carbonmonoxyhemoglobin and 8.0 in deoxyhemoglobin has been found. These pK values confirm the proposed role of histidine 146beta in the alkaline Bohr effect.

Carboxyhemoglobin

Laryngectomy.

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History, 19th Century