The Canadian medical book in the 19th century.
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Biomedical subjects
Publications and source records attributed to J J Connor.
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Adherents to American lay healer Samuel Thomson's system of medicine have been viewed in Canada primarily as antagonists of mainstream medicine. Their publishing activities, however, reveal a wide reform impulse. As this discussion illustrates by considering publishers, printers, editors, and compilers of Thomsonian books in Upper Canada, most had links--real and temperamental--to Reform politics and to dissenting Protestant beliefs, especially Methodism. Their publications may thus be viewed as vehicles for social change in a British colony having a strong Tory alliance between church and state.
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The physician-patient communication process has received little attention from library and information science (LIS) professionals. A limited review of other literature on this topic was undertaken to gain some understanding of the information exchange from an LIS perspective. The authors were interested in four issues, including how information is defined; how information-seeking behavior is portrayed; what barriers to information exist in the exchange process; and what role, if any, information plays in health outcomes. Studies have been conducted by researchers in various disciplines who have defined communication as a giving and seeking activity between the physician and the patient. Barriers to good communication, erected by either party or by both, prevent the participants from experiencing a satisfactory encounter. Because information can play a role in health outcomes, various strategies have been tried to improve the communication process. These studies provide a better understanding of the physician-patient encounter and suggest new areas of patient-centered research for LIS professionals.
The development of comprehensive pharmaceutical services for pediatric patients at a tertiary-care teaching hospital is described. A team of three staff pharmacists, a clinical specialist, and supportive personnel was formed. A pediatric pharmacy, operating from 0800 to 2100 daily, was created in a separate area of the central pharmacy to focus on potential problems with pediatric dosage calculations and drug administration. The team staffs the pediatric pharmacy for 75% of its day and evening shifts. The pharmacy prepares the 24-hour unit dose supply for each nursing unit, processes new orders, and provides drug information and problem-solving services. Clinical services are provided by the decentralized pharmacist, a rotating member of the team who makes rounds each day to the pediatric nursing units to review patient charts, provide medication information, and answer questions. The pediatric clinical specialist conducts educational programs, provides consultations, maintains reference materials, monitors pharmacokinetic evaluations, reviews medication communication forms, and assists in developing medication administration procedures. The creation of a pediatric pharmacy and a pediatric pharmacy team that coordinates both dispensing and clinical functions has made it possible to provide comprehensive pharmaceutical services to pediatric patients.
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In an assay measuring radioactive incorporation from gamma--P32P]ATP into phosphorylase b, cardiac muscle extracts from mice with the phosphorylase kinase deficiency mutation showed significant, calcium-dependent phosphorylase kinase activity that was 10 to 15% of that of Swiss mice, the control strain. Isoproterenol stimulated significant phosphorylase a accumulation in both isolated atria and right ventricular strips of phosphorylase kinase-deficient mice, and the drug-stimulated increases in phosphorylase a activity the the contractile responses of right ventricular strips were similar in Swiss and phosphorylase kinase/deficient mice.