[Regional inequalities in the consumption of opioid analgesics].
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Biomedical subjects
Publications and source records attributed to J J Criado Alvarez.
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BACKGROUND: The study investigates the temporary trend of the mortality by digestive malignant tumours in Castilla-La Mancha from 1975 to 1990. MATERIAL AND METHODS: Standardized rates were calculated by direct method, using world and european population as standard, truncated rates (35-64 years old) and cumulative rates (0-74 years old) according to tumoral location and sex. RESULTS: In both sexes the mortality by colon cancer has increased whereas the mortality by stomach cancer has decreased. These changes observed are similar with those observed in other epidemiologic studies. CONCLUSION: Driving a 15 year period a significant change in mortality due to colonic and gastric cancer has occurred in Castilla-La Mancha.
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INTRODUCTION: Attention deficit hyperactivity disorder (ADHD) is one of the most frequently occurring behavioural disorders in childhood; its prevalence in Spain is estimated to be around 3-6%. Methylphenidate (MPH) is the only medication available on the Spanish market. MATERIAL AND METHODS: The prevalence of ADHD was estimated by calculating the daily doses of MPH defined per 1000 inhabitants per day (Therapeutic group N06B A04), over the period 1992-2001, for each of the provinces in Spain. Figures for the number of prescriptions made out were obtained from the Spanish Ministry of Health and Consumer Affairs. The odds ratio and the 95% confidence interval were calculated, as was the linear tendency c2. RESULTS: A minimum prevalence of ADHD was estimated to be 0.63 per 1000 inhabitants per day for the overall Spanish population. MPH use and consumption does, however, vary with a north-south slope, and higher prevalence in Catalonia than in Andalusia. Taken as a whole, the consumption of MPH has undergone a uniform 8% increase annually since 1992, with a rising variation in the OR from 0.19 up to the year 2001 (OR = 1), and every year it has been statistically significant (c 2 = 78.246; p < 0.05). CONCLUSIONS: The consumption of MPH enables us to estimate the distribution of ADHD in Spain. The figures obtained do not yet allow us to offer an accurate estimate of the prevalence of the disease, despite the increase in consumption. Nevertheless, they do enable us to establish the variations that exist in medical practice regarding this disease.