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Biomedical subjects

J J Domanski

Publications and source records attributed to J J Domanski.

10 recordsLinked to original sources
PubMed1977

Effects of weathering and flue-curing on methomyl residues on tobacco.

A replicated field experiment was conducted at two locations to determine the disappearance of methomyl from flue-cured tobacco. Immediately after application, methomyl residues were 88 and 113 ppm at Clayton and 44 and 105 ppm at Reidsville, respectively, for 0.56 and 1.12 kg/ha application rates. After 5 days these levels dropped to 0.7 and 2.8 ppm at Clayton and 1.4 and 4.1 ppm at Reidsville. At 9 days after application, 99% of the methomyl had disappeared at both locations. Losses of methomyl during flue-curing averaged 96% over locations, rates of application, and times of harvest, compared to an average loss of 98% due to weathering in the field for 5 days. The disappearance of methomyl during the curing process was approximately the same for both locations.

Chromatography, Gas↗
PubMed1976

Human subject experiments to estimate reentry periods for monocrotophos-treated tobacco.

Thirteen to fifteen human volunteers worked for eight-hr periods in tobacco fields treated 96, 72, and 48 hr previously with monocrotophos (3-hydroxy-N-methyl-cis-crotonamide dimethyl phosphate). At the 48-hr reentry period, during which time no rainfall occurred, both post-exposure plasma and red blood cell cholinesterase levels of the worker group were depressed from pre-exposure levels although the decline was less than 9% in both cases. Rainfall in excess of one inch fell during the 96- and 72-hr reentry intervals, and no important change in cholinesterase levels was noted. Experiments with mice were in general agreement with the human tests. Dimethyl phosphoric acid in urine of the worker group collected prior to, and three hr after, exposure was unchanged in all cases. Rain appeared to have markedly reduced dislodgable residues.

Animals↗
PubMed1976

Effects of weathering and flue-curing on monocrotophos residues on tobacco.

Disappearance of monocrotophos from flue-cured tobacco was studied at three locations (Kinston, Clayton, and Reidsville, North Carolina) in 1973. Average residues on green tobacco leaves collected immediately after application were 41 and 84 ppm, respectively, for application rates of 0.56 and 1.12 kg/ha. Levels declined to about 18 and 40 ppm for the two rates three days after application, to about 9 and 23 ppm at five days, and to about three and eight ppm at nine days. Conventional curing reduced residues on flue-cured tobacco by at least 99%.

Insecticides↗
PubMed1976

Hair and its associated lipids as an excretory pathway for chlorinated hydrocarbons.

1. Chlorinated hydrocarbon insecticides and other halogenated compounds, probably biphenyls, were found to be associated with human hair at concentrations less than 1 p.p.m. 2. In experiments with rats, chlorinated 14C-hydrocarbon insecticides and polychlorinated biphenyls were excreted in hair in all instances, but excretion was less with the more labile compounds. 3. Excretion via hair may be a significant factor in eliminating chlorinated hydrocarbons which resist metabolism.

Animals↗
PubMedDate not supplied

Relation between smoking and levels of DDT and dieldrin in human fat.

The adipose tissue of humans with known patterns of cigarette smoking was collected during 1973-74 and analyzed for DDT components and dieldrin. Although smokers are exposed to high levels of insecticides from smoke of cigarettes and some of these compounds can be stored in adipose tissue, it could not be demonstrated that a relationship exists between smoking habit and residual levels of DDT found in fat. Smokers seem able, through induction of enzymes by substances in tobacco smoke, to metabolize these insecticides at a rate approximately equal to the rate of their intake in the smoke. Dieldrin residues in black male subjects were found to be linearly related to the number of cigarettes smoked, but the factors governing this relationship were not obvious.

Adipose Tissue↗