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Biomedical subjects

J J Heydenrych

Publications and source records attributed to J J Heydenrych.

At least 55 records · Page 3Linked to original sources
PubMed1983

Giant lower oesophageal ulcer in a Bushman baby. a case report.

The case of a giant, penetrating lower oesophageal ulcer in a 14-month-old Bushman baby is reported. This would probably be classified as a Barrett's ulcer. Histological examination showed that the ulcer developed in columnar epithelium and that there was normal stratified squamous oesophageal mucosa both proximally and distally to the ulcer, indicating that it had developed in an islet of ectopic gastric mucosa. The ulcer originally described by Barrett developed in a short oesophagus, into which gastric mucosa extended in a continuous sheet. Lower oesophageal ulcers should probably be divided into a primary type, of which the present case is an example, and a secondary type, in which there is direct extension of gastric mucosa into the oesophagus due to metaplasia of oesophageal mucosa secondary to reflux oesophagitis.

Black or African American↗
PubMed1983

Intraperitoneal transplantation of vascularized segmental pancreatic autografts without duct ligation in the primate.

The aim of this study was to determine whether diabetes could be ameliorated in totally pancreatectomized baboons by heterotopic intraperitoneal autotransplantation of the tail of the pancreas with the duct unligated. Twenty-five baboons were made diabetic by total pancreatectomy. Six untreated pancreatectomized animals survived a median of 5 days with mean (+/- SE) plasma glucose levels of 18 +/- 1.37 mmol/L and mean (+/- SE) potassium (K) values of 0.36 +/- 0.02% before death. Successful autotransplantation of the tail of the pancreas rendered pancreatectomized baboons consistently normoglycemic. Intravenous glucose tolerance tests performed 6 weeks after transplantation in 12 autograft recipients showed glucose intolerance in 12 of 14 recipients, and K values were significantly reduced to 1.03 +/- 0.015% (P less than 0.05). The K value of 40 normal baboons was 2.18 +/- 0.15. Histologic examination of successfully transplanted autografts of 12 animals at 6 weeks showed islets with intact beta and alpha cells, atrophy of the exocrine pancreas, graft fibrosis, and a cellular infiltration of the mononuclear type. The addition of a distal arteriovenous fistula to the graft did not reduce the incidence of graft vessel thrombosis, and all five animals died of hemorrhagic pancreatitis and venous thrombosis within 24 hours of transplantation.

Animals↗
PubMed1982

Unusual presentations of acute appendicitis in the neonate. A report of 2 cases.

Two neonates with acute appendicitis have been treated at the Paediatric Surgery Clinic, Tygerberg Hospital, during the past 6 months. One presented with red blood in the stool and had had persistent anorexia for 1 week. The second baby presented with a large tender swelling of the scrotum which was indistinguishable from a torsion of the testis or strangulation of an inguinal hernia. Both babies made an uneventful recovery.

Acute Disease↗
PubMed1982

The anatomy and movements of the pyloric sphincteric cylinder.

Disagreement about various aspects of the structure and function of the pylorus persists. Morbid anatomical, living anatomical, manometric and radiographic studies were done in an attempt to clarify some problems. It is shown that the pyloric ring (sphincteric ring) is not a separate anatomical structure, but that it constitutes the aboral end of the pyloric sphincteric cylinder, a muscular tube several centimeters in length. The ring does not function independently and conventional peristaltic waves do not proceed as far as the ring. Consequently the ring does not relax reciprocally with an oncoming peristaltic wave in the sense that a wave travels up to the ring, which relaxes upon its arrival. Each peristaltic wave stops on arrival at the oral end of the cylinder, simultaneously initiating a concentric or systolic contraction of the entire cylinder, including the ring. The cylinder, including the ring, is open at rest.

Humans↗
PubMed1982

Sonographic diagnosis of biliary ascariasis.

In a prospective 6 month study, sonographic diagnosis of biliary ascariasis was made in 12 patients: In five, the diagnosis was confirmed by other means, mainly intravenous cholangiography. In three, such confirmation was not sought, but all had proven intestinal infestation. One possible and three definite false-positive diagnoses were made. There were no established false-negative diagnoses. The echogenic, nonshadowing images of the worms were seen in the main bile duct and/or gallbladder as single strips (on one occasion with its digestive tract seen as an anechoic "inner tube"), as multiple strips giving a spaghettilike appearance, as coils, or as more amorphous fragments. Follow-up sonograms were obtained in six patients and showed expulsion of the worms by medical treatment.

Adolescent↗
PubMed1980

Herpesvirus hominis oesophagitis and oesophageal stricture.

The literature on herpetic involvement of the oesophagus is reviewed and a case is described in which the presumptive clinical diagnosis of primary Herpesvirus hominis stomatitis and oesophagitis and subsequently oesophageal strictures was made. The differential diagnosis of an oesophageal lesion and its treatment are discussed.

Child, Preschool↗
PubMed1980

Carcinoma of the breast in children: a case report and review of the literature.

The case of a 10-year-old girl with juvenile carcinoma of the breast is presented. The literature is reviewed and current thoughts relating to the treatment of breast carcinoma in children are discussed. The major controversy seems to revolve around the choice between radical and local excision in cases of juvenile or secretory breast cancer.

Breast Neoplasms↗
PubMed1979

Gliomatosis peritonei: the value of a "second look" operation.

The case history of a 10-year-old black girl with gliomatosis peritonei, Grade 0, is presented. The primary tumour was resected and a "second look" operation carried out 3 months later. The glial implants demonstrated distinct circumferential and intra glial fibrosis (resolution). Because the peritoneal implants had undergone resolution, further therapy became unnecessary. We believe gliomatosis peritonei fully justifies a second laparotomy in order to be able to accurately grade the implants. The grade of the peritoneal implants influences the prognosis and therefore determines the type of therapy to be instituted.

Child↗
PubMed1977

Bile peritonitis and miliary tuberculosis: a case report.

We report an unusual case of bile peritonitis in a child. The literature on bile peritonitis is reviewed, and its treatment is discussed. According to the literature, bile peritonitis has a good prognosis provided operation is early. Patients in whom bile is septic at the time of surgery have an increased morbidity and a considerable mortality.

Bile↗
PubMed1976

Meconium granulomas of the tunica vaginalis.

Meconium peritonitis results from perforation of the gastrointestinal tract during fetal life. Involvement of the tunica vaginalis may be the sole presenting clinical manifestation of the disease in the unusual event of the gut perforation resolving spontaneously. In such instances radiologically detectable calcification in the abdomen and scrotum is an essential diagnostic point. A case is described in which a baby had hydroceles and bilateral intrascrotal nodules but in which calcification was radiologically undetectable, presumably owing to its having undergon resolution. The typical histology of the nodules provided the diagnosis in this otherwise clinically undiagnostic case.

Calcinosis↗
PubMed1975

[Intravenous fluid therapy in paediatric surgery].

From 1956 to 1969 we adopted a generous approach pertaining to the quantity of parenteral fluid required for paediatric surgery. Since 1970 we have changed our policy, and we now give smaller quantities during surgery and postoperatively. This article presents the calculated parenteral fluid regimen as implemented for general paediatric surgery in the Tygerberg Hospital. Our reasons for this change are indicated.

Age Factors↗