Biomedical subjects

J J Higa

Publications and source records attributed to J J Higa.

7 recordsLinked to original sources

PubMed1999

Time and memory: towards a pacemaker-free theory of interval timing.

A popular view of interval timing in animals is that it is driven by a discrete pacemaker-accumulator mechanism that yields a linear scale for encoded time. But these mechanisms are fundamentally at odds with the Weber law property of interval timing, and experiments that support linear encoded time can be interpreted in other ways. We argue that the dominant pacemaker-accumulator theory, scalar expectancy theory (SET), fails to explain some basic properties of operant behavior on interval-timing procedures and can only accommodate a number of discrepancies by modifications and elaborations that raise questions about the entire theory. We propose an alternative that is based on principles of memory dynamics derived from the multiple-time-scale (MTS) model of habituation. The MTS timing model can account for data from a wide variety of time-related experiments: proportional and Weber law temporal discrimination, transient as well as persistent effects of reinforcement omission and reinforcement magnitude, bisection, the discrimination of relative as well as absolute duration, and the choose-short effect and its analogue in number-discrimination experiments. Resemblances between timing and counting are an automatic consequence of the model. We also argue that the transient and persistent effects of drugs on time estimates can be interpreted as well within MTS theory as in SET. Recent real-time physiological data conform in surprising detail to the assumptions of the MTS habituation model. Comparisons between the two views suggest a number of novel experiments.

Animals↗

PubMed1998

Temporal control in rats: analysis of nonlocalized effects from short interfood intervals.

The present experiment analyzed temporal control of postreinforcement pause duration during within-session changes in the criterion for reinforcement (interfood interval, IFI). Analysis of interval-by-interval changes in the pause revealed localized and nonlocalized effects from short intervals that caused specific changes in performance. In Phase 1, rats were presented with five consecutive 15-s IFIs intercalated into a series of 60-s IFIs. The 15-s set decreased the pause in adjacent and more remote 60-s intervals. In Phase 2, two sets of 15-s intervals were intercalated. The spacing between the two sets varied so that 0, 5, 10, or 15 60-s IFIs separated the sets. The postreinforcement pause tracked all changes in the IFI duration, and the localized effect from a short set extended beyond the next interval to the next few 60-s IFIs. Effects from one set, however, did not combine with a second set: Changes in the pause after two sets were the same regardless of the spacing between sets.

Animals↗

PubMed1996

Multiple time scales in simple habituation.

Habituation is the waning of a reflex response to repeated stimulation. Habituation to closely spaced stimuli is faster and more complete than to widely spaced stimuli, but recovery is also more rapid (rate sensitivity). We show that a 2-unit, cascaded-integrator dynamic model can explain in detail an extensive data set on rate-sensitive habituation in the nematode Caenorhabditis elegans. Many apparently complex properties of habituation and learning dynamics may reflect interactions among a small number of processes with different time scales.

Animals↗

PubMed1996

Dynamics of time discrimination: II. The effects of multiple impulses.

According to a diffusion generalization model, time discrimination is determined by the frequency and recency of preceding intervals of time. A procedure for studying rapid timing was used to investigate whether pigeons' wait-time responses were sensitive to these factors. In Experiment 1 the number (two or eight) and spacing (consecutive or far apart) of 5-s interfood intervals (called impulses) intercalated in a series of 15-s interfood intervals (nonimpulses) were studied. Experiment 2 was identical to the first but the interfood intervals were increased by a factor of three. Overall, impulses shortened wait times in the next interfood interval. However, several impulses occurring in succession extended the localized effect of an impulse: Wait times following a set of eight-close impulses were slow to recover to preimpulse levels. The results show that linear waiting is only an approximation to the dynamic process, and a process that is sensitive to events in an animal's remote past, such as the diffusion generalization model, provides a better account of rapid timing effects.

Animals↗

PubMed1993

"Transitive inference" in multiple conditional discriminations.

We used multiple conditional discriminations to study the inferential abilities of pigeons. Using a five-term stimulus series, pigeons were trained to respond differentially to four overlapping pairs of concurrently presented stimuli: A+ B-, B+ C-, C+ D-, and D+ E-, where plus and minus indicate the stimulus associated with reinforcement and extinction, respectively. Transitive inference in such situations has been defined as a preference for Stimulus B over Stimulus D in a transfer test. We measured this and other untrained preferences (A vs. C, A vs. D, B vs. E, etc.) during nonreinforced test trials. In three experiments using a novel, rapid training procedure (termed autorun), we attempted to identify the necessary and sufficient conditions for transitive inference. We used two versions of autorun: response-based, in which the subject was repeatedly presented with the least well-discriminated stimulus pair; and time-based, in which the subject was repeatedly presented with the least-experienced stimulus pair. In Experiment 1, using response-based autorun, we showed that subjects learned the four stimulus pairs faster than, but at a level comparable to, a previous study on transitive inference in pigeons (Fersen, Wynne, Delius, & Staddon, 1991), but our animals failed to show transitive inference. Experiments 2 and 3 compared time- and response-based autorun. Discrimination performance was maintained, but transitive inference was observed only on the second exposure to the response-based procedure. These results show that inferential behavior in pigeons is not a reliable concomitant of good performance on a series of overlapping discriminations. The necessary and sufficient conditions for transitive inference in pigeons remain to be fully defined.

Animals↗

PubMed1991

Dynamics of time discrimination.

Pigeons tracked sinusoidal sequences of interfood intervals (IFIs) by pausing in each interval for a time proportional to the preceding interval. Schedules with either long (30-90 s) or short (5-15 s) values, with variable numbers of cycles and starting phase each day, were tracked about equally well. Tracking was apparently immediate and did not improve across sessions. Experiment 2, in which long and short series were presented on alternate days, showed that tracking on long was more impaired than on short. Experiment 3 showed that occasional presentation of a short IFI in a series of fixed, longer IFIs caused a reduction in waiting time in the next IFI. These effects are evidence for a fast-acting timing mechanism in which waiting time in the IFI N + 1 is strongly determined by the preceding IFI, N. Earlier IFIs have some cumulative effect, but the details remain to be elucidated.

Animals↗

PubMed1989

Discrete and continuous measures of dimensional stimulus control.

In two sets of experiments, we examined dimensional stimulus control of pigeons' responses to a visual flicker-rate continuum. In the first experiment, responses to a single key were reinforced periodically during stimuli from one half of the stimulus continuum, and responses during other stimuli were extinguished. In the second experiment, two response keys were simultaneously available, with reinforcement for each response alternative associated with different halves of the stimulus continuum. Conditions of the second experiment involved either free-operant or discrete-trial stimulus presentations. Results from these experiments show that positive dimensional contrast appeared in discrimination tasks with one or two response alternatives, but only with free-operant procedures. In addition, discrimination between stimulus classes established by differential reinforcement was assessed as accurately by continuous rate measures as by discrete response choice in the two-alternative situation. The general implication of these experiments is that response rate measures, when properly applied, may reveal sources of variation within stimulus classes, such as dimensional contrast, that are not evident with discrete measures.

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