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Biomedical subjects

J J Kanski

Publications and source records attributed to J J Kanski.

17 recordsLinked to original sources

Lensectomy for complicated cataract in juvenile chronic iridocyclitis.

Experience with the removal of complicated cataract by lensectomy in patients with juvenile chronic iridocyclitis (JCI) has so far been limited. The results of lensectomy were reviewed retrospectively in 131 patients with JCI (187 eyes). The mean follow up period was 5 years 4 months. The main operative complication was accidental loss of lens material into the vitreous cavity. The postoperative complications were glaucoma (23 eyes, 15%), phthisis (14 eyes, 8%), secondary pupillary membranes (11 eyes, 6%), and retinal detachment (six eyes, 3%). The incidence of postoperative phthisis was related to the level of intraocular pressure (IOP) at the time of surgery. Twenty four per cent of hypotonous eyes and 4% of eyes with normal or elevated IOP became phthisical. Visual acuity was improved in 77%, was worse in 13%, and unchanged in 10% of eyes. The main causes of a postoperative visual acuity of 6/60 or less were glaucoma, amblyopia, and phthisis. Lensectomy did not appear to alter the course of uveitis.

Adolescent

Closed intraocular microsurgery in ocular trauma.

A series of 53 eyes that had suffered severe trauma was treated by closed intraocular microsurgery with vitreous cutters. The cases were divided into three categories: (a) anterior segment reconstruction for traumatic cataracts and post-traumatic pupillary membranes, (b) vitreous haemorrhage with and without retinal detachment, and (c) traumatically dislocated lenses.

Anterior Chamber

Anterior uveitis in juvenile rheumatoid arthritis.

The ocular and systemic characteristics of 160 patients with anterior uveitis and seronegative juvenile rheumatoid arthritis are reviewed. Chronic uveitis occurred in 131 patients, 76% of whom were girls. Both eyes were involved in 70% of the cases. Band keratopathy occurred in 41% of the eyes, cataract in 42%, and secondary glaucoma in 19%. Only 11 patients had uveitis before the onset of arthritis. Notable correlations included a pauciarticular onset of arthritis in 95% of the patients, and positive tests for antinuclear antibody in 82%. Of 29 patients with acute anterior uveitis, 27 were boys. The inflammation responded well to therapy, and serious complications did not occur. At follow-up 21 patients had typical ankylosing spondylitis, and five had sacroiliitis. The incidence of positive results of tests for HLA-B27 antigen was 94%.

Acute Disease

Vitrectomy technique in anterior segment surgery.

Instruments designed primarily for vitreous surgery were used in 74 anterior segment operations. In each case the instrument was introduced into the eye through a limbal incision. This preliminary report shows that this new approach offers several advantages over conventional methods in selected cases. It is of particular value in the management of presenile and complicated cataracts and in the removal of capsulo-lenticular remnants and pupillary membranes. A larger number of cases and longer follow-up are necessary to define further the specific indications and limitations of this technique.

Adolescent

Lensectomy.

Lensectomy is a new technique of lens extraction by which lens material is cut and aspirated through a fine-bore needle. The technique is simple and atraumatic. The small limbal incision, which does not require suturing, has the advantage of reducing the risk of vitreous loss and the amount of surgically-induced astigmatism to a minimum. Instruments designed primarily for vitreous surgery were used in the removal of cataracts from seventy eyes. This preliminary report shows that this new approach offers several advantages over conventional methods in selected cases. It appears to be of particular value in the management of cataracts secondary to chronic anterior uveitis. It is also a good alternative in the treatment of traumatic, presenile, and congenital or juvenile cataracts. Lensectomy is not a suitable technique for the removal of calcified lenses or those with hard nuclei. Possible complications include endothelial damage, loss of lens matter into the vitreous, and retinal detachment.

Adolescent

Immunoglobulins and antinuclear antibodies in aqueous humour from patients with juvenile "rheumatoid" arthritis (Still's disease).

Aqueous humour and blood from twenty cataractous patients with chronic anterior uveitis and the monopauciarticular form of juvenile rheumatoid arthritis were tested for immunoglobulins G, A, and M and for autoantibodies, particularly those against nuclear antigens. The aqueous immunoglobulins were raised in the majority of patients even when the eyes were normal biomicroscopically. Raised IgG antinuclear antibodies were found in 85% of the aqueous samples. Information obtained from the study of aqueous humour from fourteen patients with senile cataract was used for statistical analysis of these data. The presence of high molecular weight immunoglobulins in the aqueous humour from patients with Still's disease suggests an abnormal blood-ocular barrier which may be responsible for the recurrence which follows an ostensibly treated primary attack of uveitis. The presence of antinuclear antibody in a few aqueous samples without a concomitant rise in the blood levels is suggestive of local antibody synthesis.

Antibodies, Antinuclear

Prevention of aphakic retinal detachment by circumferential cryotherapy.

In a series of ARD'S, the incidence of bilaterality was 35%, as opposed to an incidence of bilaterality of 12% in patients with PRDs. The purpose of this communication is to determine whether the very high incidence of bilaterality in patients with ARDs can be reduced significantly by prophylactic treatment of the fellow eye. The fellow eye of patients who had suffered a unilateral ARDs were treated by prophylactic circumferential equatorial cryopexy irrespective of whether or not predisposing lesions were present. The eyes were treated either prior to lens extraction or following lens extraction. The techniques, complications and results of treatment are discussed.

Adult

Prophylaxis of retinal detachment.

The incidence of retinal detachment after prophylactic treatment is between 1 and 14%. In a series of 701 eyes treated prophylactically with photocoagulation or cryopexy (with and without scleral buckling), incidence of retinal detachment was 4.7%. The incidence of new break formation was 8.0%; in 26 eyes, new breaks were responsible for the subsequent formation of retinal detachment; in seven eyes, retinal detachment resulted from inadequate reaction around the treated retinal break. Twenty eyes suffered a deterioration of visual acuity of two or more lines after treatment. The incidence of complications after photocoagulation was higher than after cryopexy, although there was no significant difference in the efficacy between the two methods.

Cryosurgery

Anterior segment complications of retinal photocoagulation.

Seven patients had anterior segment complications following xenon arc retinal photocoagulation. Irreversible keratopathy was induced in two cases; all patients showed evidence of iris injury. The absorption of radiation by the iris was considered the main factor in producing overheating of the anterior segment.

Adrenal Cortex Hormones

Giant retinal tears.

Of 94 patients (100 eyes) with giant retinal tears, 71.4% of eyes with nontraumatic breaks were myopic and severe retinal pathologic findings were present in 57.3% of fellow eyes. Fifty-five (58%) of 95 treated eyes were successfully reattached; retinal incarceration, attempted in 19 cases, was successful in five. Serious surgical complications were responsible for failure in nine cases (22.5%). The worst prognostic factor were extension of the tear for over two quadrants, myopia of -10 diopters or more, and the presence of aphakia.

Adolescent

Complications of acute posterior vitreous detachment.

Of 201 patients whose presenting symptoms were acute entoptic phenomena or photopsia, or both, 150 patients had posterior vitreous detachment; 69 patients (46%) had retinal breaks; 18 (12%) had a vitreous hemorrhage without detectable retinal breaks; and two (1.3%) had peripheral retinal hemorrhages without retinal breaks or vitreous hemorrhage. Retinal breaks that occur in eyes in conjunction with acute posterior vitreous detachment are potentially dangerous and there is a possibility of delayed break formation.

Acute Disease