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J J Pindborg

Publications and source records attributed to J J Pindborg.

At least 181 records · Page 10Linked to original sources
PubMed1972

A correlative histocytological study of carcinoma and epithelial atypia of the palate among Indian reverse smokers.

A correlative histocytological study was made of 6 patients with palatal carcinomata and 342 patients with palatal lesions (primarily leukoplakias) associated with reverse smoking from the Srikakulam district of Andhra Pradesh. Among 6 histologically diagnosed carcinomata only 2 showed cytological findings typical of carcinoma. Of the 46 atypias diagnosed histologically among the other palatal lesions, only 6 (13%) were diagnosed cytologically. Our findings show that cytological examination of precancerous and cancerous lesions located on the hard palate, which is a highly keratinized area of the oral cavity, may not be reliable enough for revealing premalignant or malignant changes.

Cytodiagnosis↗
PubMed1972

Association between oral leukoplakia and sex, age, and tobacco habits.

The association between oral leukoplakia and possible etiological factors in patients at a Bombay hospital was analysed by a new multivariate computer analysis based on information theory. It was found that the most important etiological factors were bidi smoking and age. The well known sex-leukoplakia relationship was found to be secondary to sex differences in tobacco habits. The topographical distribution of leukoplakias within the oral cavity was also determined mainly by tobacco habits. It was concluded that the etiological factors analysed could not fully explain the presence or absence of leukoplakia but that other factors, so far unrecognized, may also play a role.

Adolescent↗
PubMed1971

Reverse smoking in Andhra Pradesh, India: a study of palatal lesions among 10,169 villagers.

In the district of Srikakulam in Andhra Pradesh in South India the habit of reverse smoking is widespread. In a house to house survey of oral cancer and precancerous conditions, comprising 10,169 villagers, 43·8% were reverse smokers; the female: male ratio being 1·7: 1. Ten previously undiagnosed cases of oral cancer, 9 located to palate, were found. The prevalences for leukoplakia, preleukoplakia and leukokeratosis nicotina palati were 4·9%, 2·9% and 9·5%. Of 497 leukoplakias, 422 were located to the palate and 413 of these patients had the habit of reverse smoking. Histologically, 80% of 381 palatal biopsies had a hyperorthokeratosis. Epithelial atypia was found in 15·3% of leukoplakias, in 3·6% of the preleukoplakias, and in 9·1% of leukokeratosis nicotina palati. Various explanations for the habit of reverse smoking are suggested and discussed. In addition to reverse smoking, other tobacco habits were also recorded; all habits and oral lesions were compared and have been discussed according to their apparent interrelationships and distribution by sex and age.

Adolescent↗
PubMed1971

The limitations of exfoliative cytology for the detection of epithelial atypia in oral leukoplakias.

Two hundred and ninety-nine oral leukoplakias were examined by exfoliative cytology; 83 of these lesions were biopsied because of clinical or previous histological features. Epithelial atypia was found in 16 of these biopsies, exfoliative cytology detecting epithelial atypia in only 6 of these cases. Thus exfoliative cytology used alone would have led to a false negative diagnosis in 10 out of 16 (62%) of the cases with epithelial atypia verified by histology. In addition, in no instance was exfoliative cytology responsible for the detection of an epithelial atypia that had been overlooked by consideration of clinical or previous histological features. Exfoliative cytology was successful in the detection of atypia only in those cases in which the surface of the lesion was either ulcerated or not keratinized; all keratinized lesions with atypia yielded negative cytology. The results of this study lead to the conclusion that exfoliative cytology is not to be recommended as a routine diagnostic or screening procedure for the detection of possibly pre-malignant features in oral leukoplakias.

Biopsy↗
PubMed1971

Oral leukoplakia.

Explore the source record for details and available documents.

Candidiasis, Oral↗
PubMed1970

Occurrence of epithelial atypia in 51 Indian villagers with oral submucous fibrosis.

Fifty-three biopsies from the oral mucosa in 51 Indian villagers with oral submucous fibrosis have been studied for epithelial changes. A marked atrophy of the epithelium was found in 71.7%; the atrophic epithelium showed no rete ridges. The normally unkeratinized buccal mucosa revealed either ortho- or parakeratosis or hyperortho- or hyperparakeratosis in 48.0%. In one patient the histologic examination disclosed a squamous cell carcinoma. In 22.6% an epithelial atypia was found. The histologic features in these atypias are compared with those seen in leukoplakias from the same survey. The possible precancerous nature of submucous fibrosis is discussed.

Biopsy↗