Prevalence of HIV-1 antibodies in patients attending tuberculosis clinics in Pune.
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Biomedical subjects
Publications and source records attributed to J J Rodrigues.
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Screening of blood donations for anti-HIV in western India has shown a rising trend of antibody-positive donors. There was a statistically significant difference between the proportion of positive reactors before 1986 and after 1986 (p less than 0.05).
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Brain tissues from 38 patients with a clinical suspicion of encephalitis or encephalopathy were examined by two immunoenzymatic techniques for the detection of arboviral antigen. Group B arboviral antigen was identified in 23 of these tissues. This simple method could be used for the diagnosis of the causal agent of encephalitis.
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An extensive study on tick-borne rickettsioses in the Pune district of Maharashtra revealed that Indian tick typhus exists as a zoonosis, which only occasionally causes disease in man. By sero-conversion in guinea pigs, presumptive isolates of Rickettsia conori and Coxiella burnetii were recovered from 4 of the 11 species of ticks examined. Boophilus microplus and Rhipicephalus haemaphysalis were found to be harbouring R. conori whereas C. burnetii was isolated from Haemaphysalis intermedia and Hyalomma hussaini in addition to the above mentioned 2 tick species. Complement fixation tests carried out on sera from various species of rodents and gerbils revealed the presence of antibodies against the R. conori antigen in the sera of Rattus blanfordi, R.r. rufescens and Suncus murinus. In the case of large mammals, similar antibodies were detected in the sera from dog, cow, horse and sheep. C. burnetii infection was found to exist in both the sylvan and domestic cycle, as evidenced from the involvement of ticks, large and small mammals and man in its natural history.
Recurrent peptic ulcer following surgery has been extensively studied, but its causes are not always clear. Difficulties in the differential diagnosis of the various possible factors can be very puzzling, since most of the methods described fail to provide a reliable definitive diagnosis. In the present study the authors report on the results obtained with the use of fiberoptic endoscopy complemented by biopsy of the mucosa of the duodenal stump for the diagnosis of retained gastric antrum in recurrent ulcer following B-II type gastrectomy. Considering the good results obtained with this method in 20 out of 23 patients, with a high degree of accuracy in association with biopsy and without any complications, it is strongly recommended whenever there is a possibility that retained antrum is the cause of recurrent peptic ulcer.
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