Biomedical subjects
Publications and source records attributed to J J Texier.
An experimental analogical device is described; it is able to stabilize the intracranial pressure (ICP) at an adjustable value in subjects exhibiting hydrocephalus. The mean ICP is measured by the intraventricular catheter, using a pressure measurement apparatus of conventional electric design. The result and two practical examples are presented.
Closed circuit anesthesia answers the objections to open and semi-closed systems that are related to high delivery flow rates: pollution, cost, efficiency and the hydration of inhaled gases. But closed circuit anesthesia requires a good understanding of the amount of anesthetic agenda needed, and a convenient method of administering it. It is necessary use a reliable oxygen analyser, a carbon dioxide monitor and a circuit volatile agent analyzer.
A rebreathing closed-circuit (Dräger) has been modified adjoining an automated device to inject volatile anaesthetics, thus replacing the usual vaporizer. The input of anaesthetic drug is separated from that of fresh gases: its rate of administration can thus be maintained precisely. This apparatus leads to obtain and maintain any desired concentration of the required anaesthetic. In our experiences, this device allows for a very satisfactory regulation of the alveolar concentration of the volatile anaesthetic. In addition, this apparatus is able to measure the injected volume of liquid anaesthetic and includes several devices aimed at increasing both safety and versatility.
Nimodipine was included in the treatment of four patients who had previously presented subarachnoid hemorrhage; cerebral circulation has been assayed by means of "Tomophygmographie cérébrale ultra-sonore". In all four patients, use of Nimodipine has led to an improvement of cerebral circulation and then of the neurological status. Nimodipine is characterized by its very low therapeutic inertion. Data obtained both at the initiation and on interruption of the administration of this drug points to its original properties regarding cerebral circulation: indeed, the present observations suggest that Nimodipine behaves as a true vasoregulator.
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The validity of measurement of bronchial air flow, using Wright's air flow meter, was studied comparing the maximum air flow thus obtained with the maximum expiratory volume in one second, used as unit of reference. During a first stage, the reproducibility of the test was determined this was excellent, 3.26% for the maximal flow rate and 2.48% for the maximum volume expired in one second. During a second stage were drawn up correlations between the two tests which were very narrow: O.971 in healthy sbjects, 0.919 in sick patients. The Wright flow meter is a strong, reliable and inexpensive instrument and will thus be very useful in the daily assessment of bronchiolar constriction at the bed side, and in the routine detection of obstructive syndromes.
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