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J J Viñes

Publications and source records attributed to J J Viñes.

At least 19 recordsLinked to original sources
PubMed2001

[Time trends in ovarian cancer incidence in Navarra (1973-1995): effect of age, birth cohort and period of diagnosis].

BACKGROUND: Ovarian cancer is the sixth most common malignancy and the first killer among gynaecologic cancers in women of the European Union. Five years after diagnosis relative survival rates were less than 35%. The aims of the present study are to describe the time trends in ovarian cancer incidence in Navarra over the period 1973-1995, and to identify the age, period-of-diagnosis and birth-cohort components underlying the trend's evolution. METHODS: Standard summary indexes of incidence were calculated. Log-linear Poisson models to quantify risks of ovarian cancer and the relative annual trend were used. Age-period-cohort models were adjusted in order to ascertain the effects on time trend exerted by the respective age, period-of-diagnosis and birth-cohort components. RESULTS: Ovarian cancer incidence has showed annual rises of 2.1% over the period 1973-1995, with stabilisation over the period 1988-1995. A 54% increase in the risk of ovarian cancer was shown for the period 1993-1995 vs.1973-1977. The more recent generations of women born in Navarra do not show significant changes in the risk of ovarian cancer. CONCLUSIONS: A considerable rise in ovarian cancer incidence in Navarra over the period 1973-1995 was found, less pronounced in the last decade. The risk of ovarian cancer shown in the more recent generations of women born in Navarra is stable.

English Abstract↗
PubMed1999

[Incidence of idiopathic and secondary Parkinson disease in Navarre. Population-based case registry].

AIM: To determine the incidence of Parkinson's disease in Navarra, province of Spain. PATIENTS AND METHODS: All patients diagnosed as suffering from Parkinson's disease or related disorders for the neurologists of the region during the period 1994-1995 inclusive were referred to the study. EUROPARKINSON protocol and an epidemiological questionnaire were employed for the assessment. RESULTS: A total of 132 cases of idiopathic (86) and secondary (45) Parkinson's disease were diagnosed during that period. Among men the age adjusted incidence of idiopathic Parkinson's disease was 10.06 x 10(5), while for women it was 4.92 x 10(5). Total adjusted incidence was 7.36 x 10(5). The average age at onset was 67.5 years in men and 72.6 years in women (p < or = 0.007). Men showed an age adjusted incidence of secondary parkinsonism of 3.34 x 10(5) and women of 4.23 x 10(5). Age at onset was earlier in women than in men (71.2 and 74.8 years, respectively). CONCLUSIONS: The incidence of idiopathic Parkinson's disease in Navarra is higher in men than in women, also supported for an earlier age at onset in men. The epidemiological pattern of secondary Parkinson's disease differs from that of the idiopathic disease.

Aged↗
PubMedDate not supplied

[Population-based epidemiology of colorectal cancer: causality review].

The estimated number of new cases of colorectal cancer per year in Spain (no. 19,166) is higher than other tumour locations. 1.56 times more cases of colon cancer are registered than of the rectum, and there are 1.44 times more cases in men than in women. Incidence and mortality are lower than the average for European countries; in historical series (1973-1999) an increase can be observed by age, period and birth cohorts between 1898 and 1932. On the contrary, in the USA a reduction of mortality can be observed from 1973 to 1999 (-20.8%) and of incidence from 1985 to 1999 (-7.4%). In Spain, the average duration of the disease in years is 4.29, lower than that of the European Community (4.57), and 72% of the figure for the most favourable country (5.93). Relative survival after five years in Spain is lower than in the USA (61.9% vs. 54%). Several dietary, environmental and lifestyle factors appear to be associated with colorectal cancer, but the risk or protection of these factors are of little weight and the results of studies are at times contradictory. The reduction of incidence in the USA indicates that intervention is possible to bring about a change of trend, predictably by means of secondary prevention.

Colorectal Neoplasms↗
PubMedDate not supplied

[Inverse association between smoking and idiopathic Parkinson's disease].

An evaluation is made of the effect of smoking during the period of life between 20 and 50 years of age and idiopathic Parkinson's disease in a case-control study carried out in Navarra. An inverse association is observed: for the number of smokers (OR = 0.66, CI 90% 0.41-1.05); for the number of years smoking (OR =0.22, CI 90% 0.05-0.97); and for the quantity of cigarettes smoked (z = 2.2298, p = 0.02). Likewise, a dose-response relationship exists between the number of cigarettes consumed and the risk of Parkinson's disease (p = 0.01). The same effect is maintained on analysing the data by matching 1:1 (OR = 0.59, CI 90% 0.31-1.10). All of this contributes to giving consistency to the protective effect of smoking against idiopathic Parkinson's disease. The anti-oxidant status, measured by means of different parameters in peripheral blood, is lower in the cases than in the tests for reduced glutathione (GSH) (p = 0.001) and is an independent variable with respect to smoking.

English Abstract↗
PubMedDate not supplied

[Study of the accumulation of lead in the primary teeth].

The purpose of the study was to determine the accumulation of lead in deciduous teeth in children living in the area of Pamplona (Spain). In this manner, we tried to make a relationship between the quantity of lead accumulated in the tooth against certain factors of exposure that were documented on a questionnaire carried out at the time that the tooth was presented. We analysed 457 deciduous teeth using a technique of microwave digestion follow by Atomic Absorption Spectrometry (AAS), to determine the concentration of lead in the sample. The mean lead concentration was 2.60+/-1.36 microg/g (range 0.25-10.71 microg/g). The lead concentration in our study is inferior to those observed in other European studies.

English Abstract↗