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Biomedical subjects

J Jaśkowski

Publications and source records attributed to J Jaśkowski.

At least 19 recordsLinked to original sources

Effect of air ions on healing of wounds of rat skin.

Rat skin was deprived of epidermis and the wound was exposed to ions generated with Bion 80 apparatus, for 3 h, just after wounding, only once. In comparison with the control, positive air ions retarded and negative air ions accelerated the wound healing. This effect was almost the same when air, nitrogen, oxygen and carbon dioxide were applied. A direct action of air ions is suggested.

Air↗

Effects of air ions on the membrane Na, K-ATPase activity of L 1210 cells.

The effect of exposure of L 1210 mouse leukemia cells to artificially generated air ions on the activity of membrane Na, K-ATPase in the cells was investigated. The exposure of cells to air ions of both signs gave identical results, i.e. diminution of transport activity of the enzyme, measured by radioactive 86Rb transport into the cell (ouabain-dependent). Passive ouabain-independent transport of Rb+ into the cells remained unchanged in the air ion-treated cells, as did the passive efflux of the radioisotope from preloaded cells. The possible explanation of the phenomena observed is discussed.

Air Ionization↗

Effect of air ions on L 1210 cells: changes in fluorescence of membrane-bound 1,8-aniline-naphthalene-sulfonate (ANS) after in vitro exposure of cells to air ions.

The ability of air ions to produce changes in the electrical properties of L 1210 mouse leukemia cells was tested. The fluorescence of ANS incorporated into a membrane lipid bilayer (measured microphotometrically) was used as a probe. It was shown that the action of air ions of both signs could change (negative ions by increasing and the positive ones by decreasing) the fluorescence intensity of ANS in the cell surface structures or to an imbalance of ions inside and outside the cell. Both possibilities are discussed in the light of the results of experiments using ouabain or biguanide as factors diminishing the intensity of ANS fluorescence.

Air Ionization↗