PubMed Health⌕ Search

Biomedical subjects

J Jandke

Publications and source records attributed to J Jandke.

2 recordsLinked to original sources

Unusual conjugates in biological profiles originating from consumption of onions and garlic.

After consumption of onions or garlic, biological profiles of human urine samples show, in the methylated conjugate fraction, peaks corresponding to the methylates of N-acetyl-S-(2-carboxypropyl) cysteine (1), N-acetyl-S-allylcysteine (2) and hexahydrohippuric acid (3). The compounds 1 and 2 are metabolites of peptides introduced with onions or garlic into the body.

Acetylcysteine↗

Dipeptide analysis in human urine.

Fractions of dipeptides, obtained from human urine by a combination of cation-exchange chromatography, ligand-exchange chromatography and reversed-phase chromatography, were transformed into their N-heptafluorobutyryl methyl ester derivatives and then subjected to capillary gas chromatography. The profiles obtained indicate the presence of many dipeptides in human urine. For the first time, alpha-Asp-Hyp, Pro-Phe and gamma-Glu-Phe were detected in the urine of healthy individuals.

Chromatography, Gas↗