Adenylate cyclase--properties, activity and methodology.
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Adenylyl Cyclases↗
Biomedical subjects
J Jaworska-Adamu
Publications and source records attributed to J Jaworska-Adamu.
The development of activity of lactate dehydrogenase (EC 1.1.1.27) in the areas of nigro-striatal pathway during the ontogenesis of pig.
The development of activity of lactate dehydrogenase was investigated by histochemical methods under the light and electron microscopes and also by biochemical methods. The studies were carried out in the areas of the nigro-striatal pathway of 7 foetal groups, two days-old piglets, three weeks old piglets and adult pigs. It was demonstrated that the activity of LDH appears early in the prenatal ontogenesis. High activity of the enzyme appears in the studied areas of the brain already in foetuses about 60 days old (100 mm) afterwards it rises and the highest activity is observed in about 86 days old foetuses. It then decreases just before birth. After birth in two days and three weeks old piglets the LDH activity decreases further. In adults a high activity of the examined enzyme was confirmed.
Animals↗
The development of activity of succinate dehydrogenase (EC.1.3.99.1) in the areas of the nigro-striatal pathway during the ontogenesis of a pig.
The development of activity of succinate dehydrogenase was investigated by histochemical methods under the light and electron microscopes and also by biochemical methods. The studies were carried out in the areas of the nigro-striatal pathways of 7 foetal groups, two day-old piglets, three week-old piglets and adult pigs. It was demonstrated that the activity of succinate dehydrogenase appeared first in foetuses of about 86 days (180 mm). The highest activity in prenatal development appeared just before birth in about 112 days old (260 mm) foetuses. After birth in 2 day-old piglets the activity of the examined enzyme decreases, while in 3 week-old it increases however not reaching the activity level observed in adult pigs.
Aging↗
Effect of chloramphenicol on the activity of alkaline phosphatase (EC 3.1.3.1.) and the structure of microvilli of the epithelial cells of the small intestine of the hen.
Effect of a therapeutic dose of chloramphenicol (detreomycin) on the intensity of reaction of alkaline phosphatase and on the structure of microvilli of the epithelial cells of the small intestine of the hen was investigated. It was observed that this antibiotic given orally weakened the intensity of the reaction of alkaline phosphatase and changes also the shape of microvilli of intestinal epithelium. 4 weeks after chloramphenicol administration the activity of the enzyme appeared to be normal and the morphology restored. We concluded from the experiments performed, that chloraphenicol may inhibit the process of protein glycosylation in the enterocytes of the small intestine and also weakened reversible the process of absorption.
Alkaline Phosphatase↗
[Histochemical localization of prostaglandin synthetase in various organs in swine and guinea pigs].
The activity of prostaglandin synthetase was studied according to the histochemical method of Janszen and Nugteren (1971), in author's own modification, in the lungs, arteries and parotid gland of the pig and in the same organs of the guinea pig. Additionally, the seminal vesicles of guinea pig were subject to investigation. A high activity of this enzyme has been found in the endothelial cells of the arteries in both species and a lower activity in the non-striated muscles of the artery wall. A high enzymatic activity has been also observed in the epithelial cells lining the bronchi and bronchioles of the lungs and in the ductus parotidicus of the parotid gland in both species, as well as in the epithelial cells of seminal vesicles in the guinea pig. A weaker, but distinct activity, has been observed in the cells of vesicles of pig parotid gland, and in the cells of stroma of guinea pig seminal vesicles.
Animals↗