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Biomedical subjects

J Jessop

Publications and source records attributed to J Jessop.

At least 19 recordsLinked to original sources
PubMed2006

The Pelican Cancer Foundation and The English National MDT-TME Development Programme.

The formation of The Pelican Cancer Foundation in 2000 was based around the pioneering work of Professor Bill Heald and colleagues, and the development of Total Mesorectal Excision (TME) for rectal cancer. A series of surgical workshops in Scandinavia in the mid 1990s and, later, six further workshops in the Trent region culminated in the commissioning of the fully multidisciplinary National MDT-TME Development Programme by the National Cancer Director, Professor Mike Richards, in March 2003.

Charities↗
PubMed1996

Occlusion of the external iliac vein by cement.

The case of an 80-year-old woman who sustained occlusion of the external iliac vein by methyl methacrylate cement following total hip arthroplasty is presented. The cement was removed via a pelvic approach without the need for revision of the acetabular cup and led to resolution of her symptoms.

Aged↗
PubMed1996

A nutritional assessment tool for older patients.

Older people are at increased risk of poor nutritional status. Nutritional support can improve the outcome of medical and surgical treatments and reduce length of hospital stay. Assessment is complex owing to the multifactorial nature of nutritional risk. An easily administered nutritional screening tool can be incorporated into the nursing assessment of older patients.

Aged↗
PubMed1995

An assessment tool for older patients.

A full and detailed assessment of older patients should include social circumstances. An assessment should identify problems of functional activity and use screening tools to aid referral to specialist multidisciplinary staff.

Activities of Daily Living↗
PubMed1993

Paradoxical pain.

Explore the source record for details and available documents.

Analgesics↗
PubMed1992

Evaluation of the actions of general anaesthetics in the human brain.

1. General anaesthesia is a state of analgesia and impaired cognitive function that results from the depressant effects of anaesthetics. 2. Graded increases in anaesthetic concentration cause a progressive impairment of cognitive function, the extremes of which are commonly described as "light" and "deep" anaesthesia. 3. Surgical stimulation produces activation in the EEG and may arouse a patient from a deeper to a lighter state of cognitive function. 4. It may be very difficult, particularly in patients with neuromuscular blockade, to identify a change in state which results in conscious awareness. 5. A range of methods has been used for evaluating depth of anaesthesia. 6. The evidence reviewed in this paper suggests that the median frequency in the EEG and the auditory evoked potential appear to be the best techniques for monitoring the graded effects of anaesthetics on the brain. 7. The median frequency, which is 10 Hz in conscious subjects, should be kept below 5 Hz during anaesthesia to ensure that there is no response to verbal command. 8. The auditory evoked potential measures the resulting effects of anaesthetic depression and surgical stimulation which is "depth of anaesthesia". 9. However it is not yet certain whether a particular feature e.g. Nb latency, or a collection of features between 20 and 80 msec gives the most reliable index of conscious awareness.

Anesthesia, General↗
PubMed1992

Minimizing the risk of post-operative pyoderma gangrenosum.

A 61-year-old woman with seropositive rheumatoid arthritis developed numerous ulcers due to pyoderma gangrenosum at suture entry/exit sites following an arthroplasty of the right hip when interrupted silk sutures were used to close the skin. When a subsequent arthroplasty was performed on the left hip and subcuticular Dexon sutures were used to close the skin only two small ulcers developed. Sixteen cases of pyoderma gangrenosum developing in surgical wounds have previously been reported. We recommend that surgery in patients with a history of pyoderma gangrenosum is performed when the pyoderma is clinically quiescent, and that subcuticular sutures are used for skin closure, thus avoiding puncturing the skin surface.

Adolescent↗
PubMed1992

Comparison of a direct fecal Shiga-like toxin assay and sorbitol-MacConkey agar culture for laboratory diagnosis of enterohemorrhagic Escherichia coli infection.

A direct fecal Shiga-like toxin assay (DSLTA) was used to prospectively screen 9,449 unselected stool samples, received at the British Columbia Provincial Health Laboratories and the Metropolitan Laboratories of Vancouver, for Shiga-like toxin I and Shiga-like toxin II. The results were compared with results of routine stool culture on sorbitol-MacConkey agar (SMAC) for Escherichia coli O157:H7. Of 80 specimens positive by either method, 59 (74%) and 74 (93%) were positive by SMAC and DSLTA, respectively; 53 (66%) were positive by both methods, 21 (26%) were positive by DSLTA only, and 6 (7%) were positive by SMAC only. On further screening, Shiga-like toxin-producing E. coli were detected in 8 (38%) of the 21 stools positive by DSLTA only, including serotypes O157:H7 (1 stool), O26:K60 (5 stools), O128:K67 (1 stool), and O103:H2 (1 stool). For the remaining 13 stools in which no SLTEC was found but DSLTA was positive, clinical information revealed that 11 of 12 patients had diarrheal illnesses, and 4 of these 11 had bloody diarrhea or hemolytic-uremic syndrome. Stools positive only by SMAC were collected earlier in the illness than stools positive by DSLTA, suggesting that free fecal toxin levels may be too low to detect at this time. Overall we found that DSLTA detected 19% more positive specimens than SMAC and that Shiga-like toxin-producing E. coli serotypes other than E. coli O157:H7 are causing disease in the province of British Columbia, Canada.

Bacterial Toxins↗
PubMed1991

Changes in amplitude and latency of the P300 component of the auditory evoked potential with sedative and anaesthetic concentrations of nitrous oxide.

The P300 component of the auditory evoked response was recorded from six subjects whilst they listened via headphones to a series of clicks which were interrupted unpredictably by a tone burst. They were instructed to press a button as quickly as possible after hearing the tone whilst breathing first air and then a series of increasing concentrations of nitrous oxide. Both the amplitude and the latency of the P300 changed in a dose-dependent manner with nitrous oxide, as did minimum reaction time. At nitrous oxide concentrations which prevented recall of any events that occurred whilst breathing the gas, four subjects continued to respond to the tone by pressing the button. In three subjects, the P300 wave was still detectable with a nitrous oxide concentration at which the task was no longer performed. These results show that there is retention of the ability to perform a reaction time task when there is a complete loss of recall of the task. There may be some recognition of an auditory stimulus, as manifest by a P300 wave, albeit reduced greatly in amplitude, in the absence of a motor response to it. The P300, therefore, merits investigation as a tool for studying conscious awareness under anaesthesia.

Anesthesia Recovery Period↗