Biomedical subjects
J K Aikawa
Publications and source records attributed to J K Aikawa.
Magnesium depletion as a cause of refractory potassium repletion.
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Predictors of clinical hypomagnesemia. Hypokalemia, hypophosphatemia, hyponatremia, and hypocalcemia.
Four studies were conducted, each determining the frequency of hypomagnesemia in patients already found to have one abnormal electrolyte determination. Hypomagnesemia occurred in 42% of patients with hypokalemia, 29% of patients with hypophosphatemia, 27% of patients with hyponatremia, and 22% of patients with hypocalcemia. These observations suggest that detection of either hypokalemia, hypophosphatemia, hyponatremia, or hypocalcemia, all of which are routinely available determinations, should alert the clinician to order serum magnesium determinations because of the frequent association of hypomagnesemia with these electrolyte perturbations. Optimally, levels of serum Mg should be determined on a routine basis because of the frequency of the occurrence of hypomagnesemia in hospitalized patients.
Magnesium and potassium interrelationships, experimental and clinical.
1) Coexisting Mg and K deficiency may occur with greater frequency than has been previously appreciated. 2) Profound hypokalemia, or refractoriness to K repletion or coexisting hypokalemia and hypocalcemia should suggest the possibility of concurrent Mg and K depletion. 3) The identification and treatment of concurrent K and Mg depletion is especially important in patients with congestive heart failure because of problem of digitalis toxicity. 4) We believe that the role of magnesium in optimizing cardiac function remains to be elucidated, identification and treatment of coexisting Mg and K depletion will be facilitated by making serum Mg a routine electrolyte determination together with Na, K, Cl, CO2.
Biochemistry and physiology of magnesium.
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Magnesium deficiency and refractioriness to potassium repletion.
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Editorial: Delirium tremens: a clinical example of cation pump failure?
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Proceedings: The cost-effectiveness of the C.U. computerized clinical laboratory system.
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Magnesium deficiency: a cause of reversible renal failure.
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Effect of magnesium deficiency on cardiac and skeletal muscle potassium during dietary potassium restriction.
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Alterations of serum potassium, magnesium and calcium during organ transplantation.
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Prevention of succinylcholine-induced hyperkalaemia by magnesium sulfate.
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28-Mg studies in magnesium-deficient animals.
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Fluid shifts during the surgical period: RISA and S35 determiniations following glucose, saline or lactate infusion.
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Effect of sodium salicylate on magnesium metabolism in the rabbit.
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Effect of a magnesium-deficient diet on magnesium metabolism in rabbits: a study with Mg-28.
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TRICHINELLA SKIN TESTS IN AN ORPHANAGE AND PRISON. COMPARISON WITH SEROLOGIC TESTS FOR TRICHINOSIS AND WITH THE TUBERCULIN REACTION.
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