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Biomedical subjects

J K Brooks

Publications and source records attributed to J K Brooks.

13 recordsLinked to original sources
PubMed1992

Opitz (BBB/G) syndrome: oral manifestations.

We studied a new case of the G (Opitz BBB/G) syndrome in a 12-year-old boy. Several relatives had partial manifestations of the disorder. A comprehensive dental evaluation of the propositus was conducted; included is, to our knowledge, the first published cephalometric analysis of a G syndrome patient. We reviewed 139 cases of the G syndrome; 48 of them had at least one oral abnormality. These included clefting, micrognathia, ankyloglossia, and high-arched palate. Male G syndrome patients are more likely to have oral anomalies than affected females.

Abnormalities, Multiple↗
PubMed1990

Gingival and cutaneous xanthomatosis associated with primary biliary cirrhosis. Report of a case.

The first comprehensive case report of intraoral xanthomatosis associated with primary biliary cirrhosis is detailed. The lesions were present along the free gingival margin and labial vestibule. Crevicular fluid was noted to be tinged yellow. Generalized cutaneous eruptions were also seen. The xanthomas were attributed to the underlying hyperlipoproteinemia. Advanced progression of the hepatic disease necessitated a liver transplant. Disappearance of both oral and skin lesions were subsequently observed.

Adult↗
PubMed1989

The Rieger anomaly concomitant with multiple dental, craniofacial, and somatic midline anomalies and short stature.

An unusual, isolated case of the Rieger anomaly coincident with a multitude of dental, craniofacial, and systemic anomalies is described. Significant dental findings were severe enamel hypoplasia, conical and misshapen teeth, hypodontia, and impactions. Craniofacial disorders were underdevelopment of the maxilla, mandible, and anterior and posterior cranial bases, low-set ears, and a wide nasal bridge. Reported for the first time is the association of this genetic disorder with bilateral microcondyles and bilateral choanal atresia. Embryologic disturbance of the neural crest ectoderm is suspected. The patient also manifested anal atresia, scoliosis, kyphosis, and short stature. A discussion distinguishing this case report from the Rieger syndrome is presented. In addition, the possibility that the patient exhibited a previously unreported syndrome is also considered, and the term Short-F-R-A-M-E is proposed to name this new syndrome.

Abnormalities, Multiple↗
PubMed1988

Detection of intracoronal resorption in an unerupted developing premolar: report of case.

Identification of a resorptive lesion in an unerupted premolar is detailed in this report of a 10-year-old female. The lesion was discovered during a periodic recall examination. Early detection and treatment of this resorptive process will minimize its potentially destructive capacity. Radiographic inspection of this lesion in the preeruptive dentition should be routinely performed.

Bicuspid↗
PubMed1987

The Marcus Gunn phenomenon. Discussion and report of a case.

A detailed clinical description of the Marcus Gunn phenomenon is featured. Related ophthalmologic aberrations associated with mandibular movement are briefly discussed. A report of a case of Marcus Gunn phenomenon, which was significant for a paternal history of bilateral cleft lip and palate, is presented. The general and the dental considerations in the management of this disorder are summarized. Protective eye shields are recommended for use during dental procedures.

Blepharoptosis↗
PubMed1987

Geographic stomatitis: review of the literature and report of five cases.

Five new cases of geographic stomatitis have been presented along with data from 24 previously reported patients. For the first time, basic parameters of this disorder have been tabulated from this population. Although the earliest documented case appeared in the literature in 1955, the majority of articles has been published during the last 15 years. This increased frequency of reporting indicates a growing awareness of this rather innocuous lesion. Thus, the general practitioner is advised to become familiar with the salient features of geographic stomatitis. Prompt recognition and diagnosis of this lesion, based on the clinical findings and history, will usually mitigate the need for biopsy.

Adolescent↗
PubMed1979

Enrichment of albumin and IgG in the airway secretions of dogs breathing ozone.

A study was undertaken of the acute effect of the inhalation of ozone (1.0-1.5 ppm) on the concentration of proteins in the airway secretions harvested from the trachea of intact anesthetized dogs. Secretions were first collected during a control day during which room air was breathed. The dogs breathed ozone (1.0-1.5 ppm) on a second day. This protocol permitted each dog to serve as its own control. During the inhalation of ozone the concentration of total aqueous-soluble proteins, as well as of albumin and IgG were not significantly effected. However, when expressed as a percentage of total protein, both albumin and IgG were significantly enriched in the secretions. The quantitative changes of certain proteins in airway secretions may be an important reflection of the pulmonary response to ozone.

Administration, Intranasal↗