PubMed HealthSearch

Biomedical subjects

J K Challa

Publications and source records attributed to J K Challa.

5 recordsLinked to original sources

External argon laser choroidotomy for subretinal fluid drainage.

PURPOSE: To evaluate the efficacy and safety of external argon laser choroidotomy for drainage of subretinal fluid (SRF) during scleral buckling procedures for the repair of rhegmatogenous retinal detachments. METHODS: Fifty eyes of 50 consecutive patients presenting to a hospital-based retinal outpatient clinic with rhegmatogenous detachments underwent choroidotomy with argon endolaser for SRF drainage. The laser parameters used were 0.5s duration and 0.8W power. The primary outcome measures were successful drainage of SRF and incidence of complications. The drainage was considered successful if it was sufficient to complete the planned scleral buckling procedure. The extent of subretinal haemorrhage was graded. RESULTS: The mean age of patients was 55 years (range 16-80 years). Successful drainage of SRF was obtained in 47 eyes (94%). The complications observed at the drainage site included subretinal haemorrhage of less than 1 disc diameter in six eyes (12%) and retinal perforation in one eye (2%). CONCLUSION: External argon laser choroidotomy appears to be an effective method of draining SRF in rhegmatogenous retinal detachments.

Adolescent

Exudative macular degeneration and intravitreal triamcinolone: 18 month follow up.

PURPOSE: To evaluate the safety and efficacy of intravitreal triamcinolone after 18 months of follow up in patients with age-related macular degeneration and subfoveal or juxtafoveal choroidal neovascularization considered unsuitable for laser photocoagulation. METHODS: Thirty eyes of 28 patients, referred from general eye clinics as well as the private clinic of one of the authors to a hospital-based retinal out-patient clinic, were treated with an intravitreal injection of triamcinolone (4 mg). The primary outcome measure was the proportion of eyes with loss of six or more lines on a Bailey-Lovie Chart. The incidence of adverse events associated with treatment was also observed. RESULTS: Of the 20 eyes with initial visual acuity (VA) of 6/60 or better, the vision was maintained (+/-1 Bailey-Lovie lines) in 11 eyes (55%), while six eyes (30%) suffered severe visual loss (six or more lines). The VA improved by five to six lines in three of 10 eyes with initial vision of 3/60 or worse. Three of four eyes receiving a second injection suffered either progressive cataract or elevated intra-ocular pressure (IOP) requiring cataract surgery and/or filtering surgery. One of 26 eyes (3%) receiving a single injection showed progression of cataract and elevation of IOP within 6 weeks of treatment and required anti-glaucoma medication for 6 weeks. Progression of nuclear sclerosis 8-12 months after treatment was observed in six of 26 eyes (23%) receiving a single injection. CONCLUSIONS: The results of the present study suggest that a single intravitreal injection of 4 mg triamcinolone is reasonably well tolerated by the human eye. The rate of development of severe visual loss was less than reported for historical controls. Because the results are preliminary and uncontrolled, the treatment should not be used routinely until its benefit to patients is established by a prospective, randomized controlled study.

Aged

Scleral buckling for retinal detachment. Predictors for anatomic failure.

PURPOSE: The influence of various preoperative, intraoperative, and postoperative factors on retinal reattachment after scleral buckling was examined. METHODS: A study of 601 eyes of 577 consecutive patients who underwent conventional scleral buckling procedures was conducted. Multiple logistic regression analysis was used to determine the independent influence of each variable on anatomic failure. RESULTS: Anatomic reattachment of the retina was achieved in 86% of eyes after a single procedure, and in 90% of eyes after a second surgical procedure, with a mean follow-up period of 5.27 months (range, 2-29 months). Factors predictive of poor anatomic success (P < 0.05) included preoperative choroidal detachment and significant vitreous opacification; circumferential buckle extent of more than two quadrants and intravitreal injection of air or fluid intraoperatively; and postoperative occurrence of sterile vitritis. CONCLUSION: Breakdown of the blood-retinal barrier leading to cellular migration and proliferation is considered to be predictive of anatomic failure after scleral buckling procedures.

Adolescent