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Biomedical subjects

J K Corless

Publications and source records attributed to J K Corless.

4 recordsLinked to original sources

Prospective evaluation of hospitalized patients with nonactive lower intestinal bleeding--timing and role of barium enema and colonoscopy.

A prospective evaluation of 176 hospitalized patients with nonactive lower intestinal bleeding demonstrated that a barium enema is not a necessary prerequisite for a sensitive and safe total colonoscopic examination. Colonoscopy was better in detecting colonic polyps and colon cancers than barium enema. It was concluded that colonoscopy without prior barium enema provides a sensitive diagnostic approach to hospitalized patients with nonactive lower intestinal bleeding. This approach does not interfere with the early use of angiography and may shorten hospitalization.

Adult↗

Normal liver function. A basis for understanding hepatic disease.

The physiology of the liver involves metabolism, excretion, and body defense. Within the context of metabolism, the liver is the site of a multitude of biochemical reactions essential to the human organism; included are synthesis, degradation, interconversion, storage, and biotransformation. A working knowledge of the relationship between structure and function and of hepatic processes under normal conditions is essential for understanding the derangements observed in clinical diseases affecting the liver. Our overview of hepatic physiology highlights some of these facets of normal hepatic anatomy and function of special relevance to the physician confronting liver dysfunction and its varied clinical consequences.

Amino Acids↗

Rectal sparing in antibiotic-associated pseudomembranous colitis: a prospective study.

A prospective study of 22 patients with antibiotic-associated pseudomembranous colitis demonstrated that the most distal location of the pseudomembranes was noted from 0 to 25 cm from the anus in 17 patients, from 25 to 60 cm from the anus in 3 patients, and greater than 60 cm from the anus in only 2 patients. These data suggest that the pseudomembranes will be noted by the rigid sigmoidoscope in 77% of the patients and by the flexible sigmoidoscope in 91% of the patients. Colonoscopic examination beyond 60 cm from the anus was necessary for the diagnosis of pseudomembranous colitis in 2 (9%) patients.

Adolescent↗