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J K FERGUSON

Publications and source records attributed to J K FERGUSON.

At least 19 recordsLinked to original sources
PubMed1963

SEROLOGY OF AEROBIC AQUATIC ACTINOMYCETES. II. EFFECTS OF GROWTH MEDIUM AND CULTURE AGE ON ANTIGEN LEVELS.

Guthrie, R. K. (North Texas State University, Denton), A. W. Roach, and J. K. Ferguson. Serology of aerobic aquatic actinomycetes. II. Effects of growth medium and culture age on antigen levels. J. Bacteriol. 86:173-178. 1963.-The levels of multiple antigenic components of individual isolates of aerobic actinomycetes were affected by the medium used for culture. The nutritive requirements, and the rate of growth of specific strains on a particular medium, appear to determine the number and titer of antigen components present. The antigenic components present in largest amount reached a peak titer in these organisms in 2 weeks of growth, regardless of medium. At that time, the antigenic components were present primarily in the mycelium. After 2 weeks of growth, additional components appeared in low titer, and those components in largest amount began to appear in the medium. With the appearance of antigenic components in the medium, titers of these antigens decreased in the mycelium. Standardization of conditions of growth medium and culture age served to increase the accuracy and specificity of serological grouping on the basis of reactions observed.

Actinobacteria↗
PubMed1962

Serology of aerobic aquatic Actinomycetes. I. Factors involved in antiserum production and in vitro antigen-antibody reactions.

Guthrie, R. K. (North Texas State University, Denton), A. W. Roach, and J. K. Ferguson. Serology of aerobic aquatic actinomycetes. I. Factors involved in antiserum production and in vitro antigen-antibody reactions. J. Bacteriol. 84:313-317. 1962.-The use of adjuvants permits shortening of immunization schedules, which results in improved specificity of in vitro reactions using sonically disrupted actinomycete antigenic preparations. The demonstration of specific serological reactions and of cross reactions is simplified, specificity is increased, and multiplicity of reactions is detectable by the use of agar-gel diffusion techniques in the study of individual isolates.

Actinobacteria↗